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回顾性和前瞻性研究制定腹腔镜胆囊切除术术前难度评分。

A Retrospective and Prospective Study to Develop a Pre-operative Difficulty Score for Laparoscopic Cholecystectomy.

机构信息

Gwent Centre for Digestive Diseases, Royal Gwent Hospital, Newport, Wales, NP20 2UB, UK.

出版信息

J Gastrointest Surg. 2019 Apr;23(4):690-695. doi: 10.1007/s11605-018-3821-y. Epub 2018 May 29.

Abstract

BACKGROUND

The objectives of this study were to develop a grading system to enable pre-operative prediction of technical difficulty of laparoscopic cholecystectomy using retrospective data and to attempt to validate our scoring system prospectively.

METHODS

Retrospective analysis was conducted of 100 consecutive patients. Pre-operative variables were collected based on a template devised by the American College of Surgeons. Outcomes were duration of surgery, conversion to open and post-operative complications. Multivariate analysis with subsequent measurement of hazard ratios was used to formulate a weighted grading system. Prospective analysis was performed of 100 consecutive patients who were scored pre-operatively. Outcomes were duration of surgery and length of stay.

RESULTS

Retrospective univariate analysis identified four variables associated with an increase in duration of surgery: male gender (p = 0.023), age (p = 0.000), body mass index (BMI) (p = 0.000) and pre-operative endoscopic retrograde cholangiopancreatography (ERCP) (p = 0.001). Prospective analysis revealed weak positive correlations between the scoring system and duration of surgery (0.34) and length of stay (0.40).

CONCLUSION

We have identified four pre-operative variables that predicted a longer duration of surgery. Preliminary results suggest a positive correlation between this scoring system and duration of surgery. An adequately powered prospective multi-centre study is needed to validate our findings.

摘要

背景

本研究旨在开发一种分级系统,以便利用回顾性数据对腹腔镜胆囊切除术的技术难度进行术前预测,并尝试对我们的评分系统进行前瞻性验证。

方法

对 100 例连续患者进行回顾性分析。根据美国外科医师学院制定的模板收集术前变量。手术时间、中转开腹和术后并发症作为观察指标。采用多变量分析和随后的风险比测量来制定加权分级系统。对 100 例连续患者进行前瞻性分析,这些患者在术前进行了评分。手术时间和住院时间作为观察指标。

结果

回顾性单因素分析确定了四个与手术时间延长相关的变量:男性(p=0.023)、年龄(p=0.000)、体重指数(BMI)(p=0.000)和术前内镜逆行胰胆管造影(ERCP)(p=0.001)。前瞻性分析显示评分系统与手术时间(0.34)和住院时间(0.40)之间存在弱正相关。

结论

我们已经确定了四个可预测手术时间延长的术前变量。初步结果表明,该评分系统与手术时间之间存在正相关。需要进行一项足够大的前瞻性多中心研究来验证我们的发现。

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