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关于膳食纤维抗性淀粉的抗糖尿病和抗肥胖作用的评论性综述。

A critical review on anti-diabetic and anti-obesity effects of dietary resistant starch.

机构信息

Food Science and Technology Program, Beijing Normal University-Hong Kong Baptist University United International College , Zhuhai , China.

出版信息

Crit Rev Food Sci Nutr. 2019;59(18):3019-3031. doi: 10.1080/10408398.2018.1481360. Epub 2018 Jul 9.

DOI:10.1080/10408398.2018.1481360
PMID:29846089
Abstract

"Diabesity" is the term to illustrate the interdependent relationship between obesity and diabetes. About 80% of the diabetic patients are diagnosed with obesity. Diabesity can be prevented by dietary interventions, especially by incorporating sufficient amount of resistant starch (RS). In the past few decades, RS has inspired the researchers due to its various health benefits. Differing from digestible starch, RS remains undigested in the small intestine, but in the large intestine, it is subjected to fermentation. This review intends to encapsulate the current information related to the dietary RS on diabetes and obesity. RS attenuate hyperglycemic, hyperinsulinemic and hyperlipidemic response in various subjects by restricting gluconeogenesis, bolstering glycogenesis, maintaining glucose and lipid homeostasis and ameliorating pancreatic dysfunction. Various food products were fortified with RS to enhance its dietary intake and were found to exhibit positive impact on human and animal models. This review identified and summarized the research gaps in the available literature.

摘要

“糖胖病”是指肥胖症和糖尿病之间相互依存的关系。约 80%的糖尿病患者被诊断为肥胖症。糖胖病可以通过饮食干预来预防,尤其是通过摄入足够量的抗性淀粉(RS)。在过去几十年中,RS 因其多种健康益处而激发了研究人员的兴趣。与可消化淀粉不同,RS 在小肠中未被消化,但在大肠中,它会被发酵。本篇综述旨在总结与饮食 RS 对糖尿病和肥胖相关的最新信息。RS 通过限制糖异生、增强糖生成、维持血糖和脂质平衡以及改善胰腺功能障碍,减轻各种研究对象的高血糖、高胰岛素血症和高血脂反应。各种食品都添加了 RS,以增加其饮食摄入,并在人体和动物模型中发现了积极的影响。本综述确定并总结了现有文献中的研究空白。

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