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抗性淀粉降血糖机制的研究进展:综述。

Research Progress on Hypoglycemic Mechanisms of Resistant Starch: A Review.

机构信息

Key Laboratory of Agro-Products Quality and Safety Control in Storage and Transport Process, Ministry of Agriculture and Rural Affairs, Institute of Food Science and Technology, Chinese Academy of Agricultural Sciences, Beijing 100193, China.

College of Food Science and Technology, Hebei Agricultural University, Baoding 071033, China.

出版信息

Molecules. 2022 Oct 21;27(20):7111. doi: 10.3390/molecules27207111.

Abstract

In recent years, the prevalence of diabetes is on the rise, globally. Resistant starch (RS) has been known as a kind of promising dietary fiber for the prevention or treatment of diabetes. Therefore, it has become a hot topic to explore the hypoglycemic mechanisms of RS. In this review, the mechanisms have been summarized, according to the relevant studies in the recent 15 years. In general, the blood glucose could be regulated by RS by regulating the intestinal microbiota disorder, resisting digestion, reducing inflammation, regulating the hypoglycemic related enzymes and some other mechanisms. Although the exact mechanisms of the beneficial effects of RS have not been fully verified, it is indicated that RS can be used as a daily dietary intervention to reduce the risk of diabetes in different ways. In addition, further research on hypoglycemic mechanisms of RS impacted by the RS categories, the different experimental animals and various dietary habits of human subjects, have also been discussed in this review.

摘要

近年来,糖尿病的患病率在全球呈上升趋势。抗性淀粉(RS)作为一种有前途的膳食纤维,已被广泛用于预防或治疗糖尿病。因此,探索 RS 的降血糖机制已成为研究热点。本综述总结了近 15 年来相关研究中 RS 的降血糖机制,主要包括通过调节肠道菌群紊乱、抗消化、减轻炎症、调节降糖相关酶等方式来调节血糖。虽然 RS 发挥有益作用的确切机制尚未完全证实,但研究表明 RS 可作为一种日常饮食干预措施,通过多种方式降低糖尿病的发病风险。此外,本文还讨论了 RS 类别、不同实验动物以及人类不同饮食习惯对 RS 降血糖机制的影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4f35/9610089/d2addc4b7fab/molecules-27-07111-g001.jpg

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