Ibba M, Mennini T, Testa R
Pharmacol Res Commun. 1985 Jan;17(1):95-103. doi: 10.1016/0031-6989(85)90055-4.
Denzimol, a new anticonvulsant drug, enhances the depressant and antimetrazol activities of diazepam in mice, in a dose and time-dependent fashion. The depressant and anticonvulsant activities of phenobarbital were not affected by Denzimol. It is suggested that Denzimol induces an increase in the number of the benzodiazepine receptors, and that such increase might be responsible for the enhancement of the diazepam's activities.
丹齐莫尔是一种新型抗惊厥药物，它能以剂量和时间依赖性方式增强地西泮对小鼠的抑制作用及抗戊四氮活性。苯巴比妥的抑制和抗惊厥活性不受丹齐莫尔影响。有研究表明，丹齐莫尔可诱导苯二氮䓬受体数量增加，这种增加可能是其增强地西泮活性的原因。
