Hagi Tomohito, Nakamura Tomoki, Sugino Yuichi, Matsubara Takao, Asanuma Kunihiro, Sudo Akihiro
Department of Orthopaedic Surgery, Mie University Graduate School of Medicine, Tsu, Japan.
Department of Orthopaedic Surgery, Mie University Graduate School of Medicine, Tsu, Japan
Anticancer Res. 2018 Jun;38(6):3635-3639. doi: 10.21873/anticanres.12638.
BACKGROUND/AIM: In patients with soft tissue sarcoma (STS), distinguishing small metastatic pulmonary nodules from benign ones remains difficult. This study aimed to determine the accuracy of F-fluorodeoxyglucose positron emission tomography/computed tomography (FDG-PET/CT) in detecting pulmonary metastasis and identify factors affecting sensitivity with STS.
The clinical records and chest CT and FDG-PET/CT scans of 102 patients with STS were reviewed to determine the presence of pulmonary nodules.
A significant relationship was observed between nodule size and maximum standardized uptake value (SUV). For nodules smaller than 5 mm, only 10 out of 76 metastatic pulmonary nodules exhibited FDG accumulation, showing a weak correlation between nodule size and SUV Conclusion: The role of FDG-PET/CT in differentiating metastatic from benign pulmonary nodules was unsatisfactory, especially for small nodules. Careful follow-up using CT scan may still be appropriate for diagnosing pulmonary nodules smaller than 5 mm.
背景/目的：在软组织肉瘤（STS）患者中，区分小的肺转移结节和良性结节仍然困难。本研究旨在确定F-氟脱氧葡萄糖正电子发射断层扫描/计算机断层扫描（FDG-PET/CT）检测肺转移的准确性，并确定影响STS患者敏感性的因素。
回顾102例STS患者的临床记录、胸部CT和FDG-PET/CT扫描结果，以确定肺结节的存在情况。
观察到结节大小与最大标准化摄取值（SUV）之间存在显著相关性。对于小于5mm的结节，76个肺转移结节中只有10个表现出FDG摄取，提示结节大小与SUV之间的相关性较弱。结论：FDG-PET/CT在区分肺转移结节和良性结节方面的作用并不理想，尤其是对于小结节。对于小于5mm的肺结节，使用CT扫描进行仔细随访可能仍然是合适的诊断方法。
