Joulaeerad Narges, Ozgoli Giti, Hajimehdipoor Homa, Ghasemi Erfan, Salehimoghaddam Fatemeh
Student Research Committee, Department of Midwifery and Reproductive Health, School of Nursing and Midwifery, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Midwifery and Reproductive Health Research Center, Department of Midwifery and Reproductive Health, School of Nursing and Midwifery, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
J Reprod Infertil. 2018 Jan-Mar;19(1):32-38.
Nausea and vomiting are common complaints in the first half of pregnancy. These symptoms can significantly affect a person's personal and professional life. Aromatherapy is one of the types of complementary medicine that is used in the treatment of nausea and vomiting. The objective of this study was to determine the effect of aromatherapy with peppermint oil on the severity of nausea and vomiting of pregnancy (NVP).
This was a single-blind clinical trial that was conducted on 56 pregnant women with mild to moderate severity of NVP and 6 to 20 weeks of gestational age. After the determination of gestational age and base severity of NVP in each woman, they were randomly assigned to one of the two groups: peppermint oil (n=28) or placebo (n=28). Inhalation aromatherapy was done for four days and at the end of each day, they responded to the Pregnancy Unique Quantification of Emesis/Nausea questionnaire (PUQE). The data obtained were analyzed with Mann-Whitney test and ANOVA with repeated measures using SPSS software version 22. Also, the level of significance was p<0.05.
Although the severity of NVP in each intervention group significantly decreased (p<0.001), the comparison of the severity of NVP during the study period and at the end of it was not statistically significant between the placebo and intervention groups.
According to the possibility of neurological mechanisms causing NVP, the effect of aromatherapy with peppermint oil and placebo were the same in this study. This similarity can be due to psychological impacts of intervention on pregnant women.
恶心和呕吐是妊娠前半期常见的症状。这些症状会显著影响个人和职业生活。芳香疗法是用于治疗恶心和呕吐的补充医学类型之一。本研究的目的是确定薄荷油芳香疗法对妊娠恶心和呕吐（NVP）严重程度的影响。
这是一项单盲临床试验，对56名妊娠6至20周、NVP为轻度至中度的孕妇进行。在确定每位女性的孕周和NVP基础严重程度后，她们被随机分为两组之一：薄荷油组（n = 28）或安慰剂组（n = 28）。进行为期四天的吸入式芳香疗法，每天结束时，她们要对妊娠呕吐/恶心独特量化问卷（PUQE）做出回应。使用SPSS 22版软件，通过曼-惠特尼检验和重复测量方差分析对获得的数据进行分析。显著性水平为p<0.05。
尽管每个干预组的NVP严重程度均显著降低（p<0.001），但在研究期间及结束时，安慰剂组和干预组之间NVP严重程度的比较无统计学意义。
根据导致NVP的神经机制可能性，本研究中薄荷油芳香疗法和安慰剂的效果相同。这种相似性可能是由于干预对孕妇的心理影响。
