Kotova E N
Biull Eksp Biol Med. 1985 Mar;99(3):303-6.
Using repeated operative biopsies the author examined changes in the concentration of cytochromes a, b, c1 and c in mitochondrial protein of hepatocytes during the development of cirrhosis in rabbit liver. Individual responsiveness was discovered at the level of enzymatic constitution of the mitochondria, that is in the shifts in the specific weight of the respiratory chains in the protein of these organelles.
作者通过反复进行手术活检,研究了兔肝肝硬化发展过程中肝细胞线粒体蛋白中细胞色素a、b、c1和c浓度的变化。发现线粒体酶组成水平存在个体反应性,即在这些细胞器蛋白中呼吸链比重的变化。