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[甲状腺激素对雏鸡个体发育过程中肝脏和心脏组织细胞色素浓度的影响]

[Effect of thyroid hormones on cytochrome concentration on the liver and heart tissues of chickens during ontogenesis].

作者信息

Khamidov D Kh, Shulakova T Iu, Dul'man R A

出版信息

Ontogenez. 1977;8(2):144-9.

PMID:198716
Abstract

Changes in the concentration of cytochromes c, c1 and a in the liver and heart homogenates during chick pre- and postnatal development were detected by means of low temperature differential spectrometry. At the early stages of development the high content of respiratory enzymes comparable with that in the adult organism is noted. By the end of embryogenesis the content of cytochromes decreased and, subsequently, increased. The injection of thyroxine in the 16-17 days old embryos and 9-10 days old chickes resulted in more distinct changes in the content of respiratory enzymes in mitochondria of the heart, as compared with those of the liver. No changes in the content of cytochromes were recorded after the injection of 6-methyl thiouracyl in the 10 days old embryos, thus suggesting the inactive state of thyroid parenchyma during this period of development.

摘要

利用低温差光谱法检测了雏鸡出生前后肝脏和心脏匀浆中细胞色素c、c1和a浓度的变化。在发育早期,观察到呼吸酶的含量与成年生物体相当高。到胚胎发育结束时,细胞色素的含量下降,随后又上升。与肝脏相比,在16 - 17日龄胚胎和9 - 10日龄雏鸡中注射甲状腺素导致心脏线粒体中呼吸酶含量发生更明显的变化。在10日龄胚胎中注射6 - 甲基硫脲嘧啶后,未记录到细胞色素含量的变化,这表明在此发育阶段甲状腺实质处于无活性状态。

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