Aizenberg D, Shalev A, Munitz H
Br J Psychiatry. 1985 Mar;146:317-8. doi: 10.1192/bjp.146.3.317.
The neuroleptic malignant syndrome (NMS) is an idiosyncratic reaction to neuroleptic drugs, made up of hyperthermia, muscular rigidity, disturbance of level of consciousness and autonomic dysfunction. It is potentially lethal and should be kept in mind whilst using anti-psychotic drugs; as most patients treated by them require further anti-psychotic treatment, the clinician faces the problem of treating those patients after a NMS episode, yet reports in the literature have generally neglected the problem of late management. A patient suffering from a psychosis and NMS is presented, and a rationale for management offered.
神经阻滞剂恶性综合征（NMS）是对神经阻滞剂药物的一种特异反应，由高热、肌肉强直、意识水平障碍和自主神经功能障碍组成。它有潜在的致命性，在使用抗精神病药物时应予以关注；由于大多数接受这些药物治疗的患者需要进一步的抗精神病治疗，临床医生面临着在NMS发作后治疗这些患者的问题，然而文献报道普遍忽视了后期管理的问题。本文介绍了一名患有精神病和NMS的患者，并提供了管理的基本原理。
