Kafka M S, Marangos P J, Moore R Y
Brain Res. 1985 Feb 18;327(1-2):344-7. doi: 10.1016/0006-8993(85)91533-1.
The effect of suprachiasmatic nucleus (SCN) ablation on rhythms in brain neurotransmitter receptors was studied. In control animals, the rhythms in the number of alpha-adrenergic and benzodiazepine receptors were circadian, whereas the rhythms in beta-adrenergic and acetylcholine receptors were ultradian. SCN ablation resulted in loss of circadian, but not ultradian, rhythms, without change in the 24-h mean numbers. SCN ablation appears to cause a selective loss of circadian function in the regulation of brain receptors.
研究了视交叉上核(SCN)消融对脑神经递质受体节律的影响。在对照动物中,α-肾上腺素能受体和苯二氮䓬受体数量的节律是昼夜节律性的,而β-肾上腺素能受体和乙酰胆碱受体的节律是超日节律性的。SCN消融导致昼夜节律而非超日节律丧失,24小时平均数量无变化。SCN消融似乎在脑受体调节中导致昼夜节律功能的选择性丧失。