一种已鉴定的软体动物神经元被动膜特性的发育变化。

Developmental changes in the passive membrane properties of an identified molluscan neuron.

作者信息

Pawson P A, Chase R

出版信息

Brain Res. 1985 Jan;349(1-2):296-300. doi: 10.1016/0165-3806(85)90159-2.

Abstract

We have studied developmentally the electrotonic fate of synaptic potentials in an identified giant neuron of the Pulmonate mollusc Achatina fulica. Our experimental preparation enabled us to sample spontaneously occurring excitatory postsynaptic potentials (EPSPs) from embryogenesis onward, while concomitantly analyzing the postsynaptic membrane properties. We observe non-monotonic changes in the electrotonic attenuation of synaptic inputs which invade the somata. Our data suggest that non-monotonic changes in the specific membrane resistance can account for these observations.

摘要

我们已经从发育角度研究了肺螺亚纲软体动物非洲大蜗牛一个已鉴定的巨型神经元中突触电位的电紧张命运。我们的实验准备工作使我们能够从胚胎发生开始就采集自发出现的兴奋性突触后电位（EPSP），同时分析突触后膜特性。我们观察到侵入胞体的突触输入在电紧张衰减方面出现非单调变化。我们的数据表明，比膜电阻的非单调变化可以解释这些观察结果。