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入住心脏病诊所的高龄土耳其患者的心血管疾病患病率、危险因素及心血管药物治疗:ELDER-TURK研究的亚组分析。

The prevalence of cardiovascular diseases, risk factors, and cardiovascular drug therapy in very elderly Turkish patients admitted to cardiology clinics: A subgroup analysis of the ELDER-TURK study.

作者信息

Gök Gülay, Sinan Ümit Yaşar, Özyüncü Nil, Zoghi Mehdi

机构信息

Department of Cardiology, Mardin State Hospital, Mardin, Turkey.

出版信息

Turk Kardiyol Dern Ars. 2018 Jun;46(4):283-295. doi: 10.5543/tkda.2018.49579.

DOI:10.5543/tkda.2018.49579
PMID:29853696
Abstract

OBJECTIVE

The aim of this study was to determine the baseline clinical characteristics and the cardiovascular drug usage of patients aged ≥80 years who were admitted to cardiology clinics and to compare the cardiovascular disease and risk factors with patients aged 65-79 years who participated in the Epidemiology of Cardiovascular Disease in Elderly Turkish Population (ELDER-TURK) study.

METHODS

The ELDER-TURK study included 5694 patients aged over 65 years who were followed up at cardiology clinics between March 2015 and December 2015. The prevalence of cardiovascular diseases and the risk factors of 1098 patients aged ≥80 years (Group II) were compared with 4596 patients aged 65-79 years (Group I).

RESULTS

The mean age of Group I was 71.1±4.31 years (male: 50.2%) and the mean age of Group II was 83.5±3.12 years (male: 47.5%). The prevalence rate was 71.3% for hypertension, 24.6% for diabetes mellitus (DM), 44.7% for coronary artery disease (CAD), 35.9% for atrial fibrillation (AF), and 15.5% for renal failure. A statistical difference in the prevalence of comorbid conditions and cardiovascular disease risk factors, such as DM, CAD, renal failure, and AF was seen in the very elderly group (p<0.001, p=0.002, p<0.001, p<0.001, respectively). In all, 28.7% of the very elderly were using a beta-blocker, 10.1% an angiotensin system inhibitor, 28.4% an angiotensin receptor blocker, and 32.7% a mineralocorticoid receptor antagonist.

CONCLUSION

Valuable data about the prevalence of cardiovascular and comorbid diseases and medication usage among Turkey`s very elderly patients who were admitted to cardiology clinics was gathered and analyzed.

摘要

目的

本研究旨在确定入住心脏病诊所的80岁及以上患者的基线临床特征和心血管药物使用情况,并将其心血管疾病及危险因素与参与土耳其老年人群心血管疾病流行病学(ELDER-TURK)研究的65-79岁患者进行比较。

方法

ELDER-TURK研究纳入了2015年3月至2015年12月期间在心脏病诊所接受随访的5694名65岁以上患者。将1098名80岁及以上患者(第二组)的心血管疾病患病率和危险因素与4596名65-79岁患者(第一组)进行比较。

结果

第一组的平均年龄为71.1±4.31岁(男性:50.2%),第二组的平均年龄为83.5±3.12岁(男性:47.5%)。高血压患病率为71.3%,糖尿病(DM)患病率为24.6%,冠状动脉疾病(CAD)患病率为44.7%,心房颤动(AF)患病率为35.9%,肾衰竭患病率为15.5%。在高龄组中,DM、CAD、肾衰竭和AF等合并症和心血管疾病危险因素的患病率存在统计学差异(分别为p<0.001、p=0.002、p<0.001、p<0.001)。总体而言,高龄患者中28.7%使用β受体阻滞剂,10.1%使用血管紧张素系统抑制剂,28.4%使用血管紧张素受体阻滞剂,32.7%使用盐皮质激素受体拮抗剂。

结论

收集并分析了有关入住土耳其心脏病诊所的高龄患者心血管和合并疾病患病率及药物使用情况的宝贵数据。

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