Department of Anesthesiology, Chang Gung Memorial Hospital, Taoyuan, Taiwan.
College of Medicine, Chang Gung University, Taoyuan, Taiwan.
Biomed Res Int. 2018 May 2;2018:8582901. doi: 10.1155/2018/8582901. eCollection 2018.
The aim of this population-based cohort study was to explore postoperative renal outcomes of patients receiving pyelolithotomy versus percutaneous nephrolithotomy (PCNL). Data were retrieved from the Taiwan National Health Insurance Research Database. During the period from Jan 1, 1998, to Dec 31, 2012, there were 2549 and 21654 patients who underwent pyelolithotomy and PCNL, respectively. The postoperative incidence of new diagnosed end stage renal disease (ESRD) was statistically analyzed and compared between the pyelolithotomy and PCNL groups. The perioperative complications of two groups were also analyzed. In comparison to pyelolithotomy, PCNL achieved lower new diagnosed ESRD (1.38% versus 2.28%, = 0.0004). Patients receiving PCNL had significantly higher rates of preoperative hypertension, diabetes mellitus, pulmonary disease, cerebrovascular disease, and coronary artery disease. The hospital stay was shorter in PCNL groups compared with pyelolithotomy groups (8.31 days versus 12.59 days, = 0.0006). In conclusion, PCNL contributed to lower rates of new diagnosed ESRD and hospital stay when compared to pyelolithotomy.
本基于人群的队列研究旨在探讨接受肾盂切开取石术与经皮肾镜碎石术（PCNL）的患者的术后肾脏结局。数据来自台湾全民健康保险研究数据库。1998 年 1 月 1 日至 2012 年 12 月 31 日期间，分别有 2549 例和 21654 例患者接受了肾盂切开取石术和 PCNL。对两组术后新发终末期肾病（ESRD）的发生率进行了统计学分析和比较。还分析了两组的围手术期并发症。与肾盂切开取石术相比，PCNL 新发 ESRD 的发生率较低（1.38%比 2.28%， = 0.0004）。接受 PCNL 的患者术前高血压、糖尿病、肺部疾病、脑血管疾病和冠状动脉疾病的发生率明显更高。与肾盂切开取石术组相比，PCNL 组的住院时间更短（8.31 天比 12.59 天， = 0.0006）。总之，与肾盂切开取石术相比，PCNL 可降低新发 ESRD 发生率和住院时间。
