Department of Surgery, Faculty of Medicine, Thammasat University (Rangsit Campus), 95 Moo 8, Paholyothin Road, Amphur Klongluang, Rangsit, Pathumthani, 12120, Thailand.
J Gastrointest Surg. 2018 Oct;22(10):1659-1664. doi: 10.1007/s11605-018-3822-x. Epub 2018 May 31.
Publications document the risk of developing esophageal stricture as a sequential complication of esophageal injury grades 2b and 3a. Although there are studies describing the risk factors of post-corrosive stricture, there is limited literature on these factors. The aim of this study was to evaluate the different factors with post-corrosive esophageal stricture and non-stricture groups in endoscopic grades 2b and 3a of corrosive esophageal injuries.
Data were retrospectively analyzed in the patients with esophageal injury grades 2b and 3a between January 2011 and December 2017.
One hundred ninety-six corrosive ingestion patients were admitted with 32 patients (15.8%) in grade 2b and 12 patients (6.1%) in grade 3a and stricture was developed in 19 patients (61.3%) with grade 2b and in 10 patients (83.3%) with grade 3a. The patients' height of the non-stricture group was greater than that of stricture groups (2b stricture group, 1.58 ± 0.08 m; 2b non-stricture group, 1.66 ± 0.07 m; p < 0.004; 3a stricture group, 1.52 ± 0.09 m; 3a non-stricture group, 1.71 ± 0.02 m; p < 0.001). Omeprazole was more commonly used in the non-stricture than stricture group (26.3% in the 2b stricture group, 69.2% in the 2b non-stricture group, p = 0.017; 50% in the 3a stricture group, 100% in the 3a non-stricture group, 1.71 ± 0.02 m, p = 0.015).
The height of patients may help to predict the risks and the prescription of omeprazole may help to minimize the risks of 2b and 3a post-corrosive esophageal stricture.
文献报道食管损伤 2b 级和 3a 级是食管狭窄的顺序并发症。虽然有研究描述了腐蚀性狭窄的危险因素，但关于这些因素的文献有限。本研究旨在评估腐蚀性食管损伤内镜 2b 级和 3a 级中腐蚀性食管狭窄和非狭窄组的不同因素。
回顾性分析 2011 年 1 月至 2017 年 12 月期间食管损伤 2b 级和 3a 级的患者。
196 例腐蚀性摄入患者中，2b 级患者 32 例（15.8%），3a 级患者 12 例（6.1%），2b 级患者中有 19 例（61.3%）出现狭窄，3a 级患者中有 10 例（83.3%）出现狭窄。非狭窄组患者的身高大于狭窄组（2b 狭窄组，1.58±0.08m；2b 非狭窄组，1.66±0.07m；p<0.004；3a 狭窄组，1.52±0.09m；3a 非狭窄组，1.71±0.02m；p<0.001）。非狭窄组比狭窄组更常使用奥美拉唑（2b 狭窄组 26.3%，2b 非狭窄组 69.2%，p=0.017；3a 狭窄组 50%，3a 非狭窄组 100%，p=0.015）。
患者的身高可能有助于预测风险，奥美拉唑的处方可能有助于降低 2b 级和 3a 级腐蚀性食管狭窄的风险。
