Accelerated biological aging in serious mental disorders.
作者信息
Wolkowitz Owen M
机构信息
University of California San Francisco School of Medicine, San Francisco, CA, USA.
出版信息
World Psychiatry. 2018 Jun;17(2):144-145. doi: 10.1002/wps.20546.
Abstract
摘要
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本文引用的文献
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The epigenetic clock and telomere length are independently associated with chronological age and mortality.表观遗传时钟和端粒长度与实足年龄及死亡率独立相关。
Int J Epidemiol. 2018 Feb 1;47(1):356. doi: 10.1093/ije/dyx233.
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Excess mortality in persons with severe mental disorders: a multilevel intervention framework and priorities for clinical practice, policy and research agendas.严重精神障碍患者的超额死亡率：一个多层次干预框架以及临床实践、政策和研究议程的优先事项
World Psychiatry. 2017 Feb;16(1):30-40. doi: 10.1002/wps.20384.
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Lifetime stress accelerates epigenetic aging in an urban, African American cohort: relevance of glucocorticoid signaling.终生压力会加速城市非裔美国人队列中的表观遗传衰老：糖皮质激素信号传导的相关性。
Genome Biol. 2015 Dec 17;16:266. doi: 10.1186/s13059-015-0828-5.
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Telomerase activation as a possible mechanism of action for psychopharmacological interventions.端粒酶激活作为精神药理学干预作用的一种可能机制。
Drug Discov Today. 2015 Nov;20(11):1305-9. doi: 10.1016/j.drudis.2015.06.016. Epub 2015 Jul 9.
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Psychiatric disorders and leukocyte telomere length: Underlying mechanisms linking mental illness with cellular aging.精神疾病与白细胞端粒长度：将精神疾病与细胞衰老联系起来的潜在机制。
Neurosci Biobehav Rev. 2015 Aug;55:333-64. doi: 10.1016/j.neubiorev.2015.05.007. Epub 2015 May 18.
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Telomere length and cortisol reactivity in children of depressed mothers.抑郁症母亲的子女的端粒长度与皮质醇反应性
Mol Psychiatry. 2015 May;20(5):615-20. doi: 10.1038/mp.2014.119. Epub 2014 Sep 30.
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DNA methylation age of human tissues and cell types.人类组织和细胞类型的DNA甲基化年龄
Genome Biol. 2013;14(10):R115. doi: 10.1186/gb-2013-14-10-r115.
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Pathways to aging: the mitochondrion at the intersection of biological and psychosocial sciences.衰老的途径：处于生物科学与心理社会科学交叉点的线粒体
J Aging Res. 2011;2011:814096. doi: 10.4061/2011/814096. Epub 2011 Sep 26.
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Of sound mind and body: depression, disease, and accelerated aging.身心健康：抑郁症、疾病与加速衰老。
Dialogues Clin Neurosci. 2011;13(1):25-39. doi: 10.31887/DCNS.2011.13.1/owolkowitz.
10
Telomerase reactivation reverses tissue degeneration in aged telomerase-deficient mice.端粒酶重新激活可逆转端粒酶缺陷型老年小鼠的组织退化。
Nature. 2011 Jan 6;469(7328):102-6. doi: 10.1038/nature09603. Epub 2010 Nov 28.
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