College of Food Science and Engineering , Qingdao Agricultural University , 700 Changcheng Road , Chengyang District, Qingdao , Shandong Province 266109 , China.
J Agric Food Chem. 2018 Jun 20;66(24):6104-6115. doi: 10.1021/acs.jafc.8b01890. Epub 2018 Jun 11.
The pursuit of sustainable functional materials requires the development of materials based on renewable resources and efficient fabrication methods. Here, we first fabricated chitosan-sodium phytate films via one-step-stripping and layer-by-layer-casting technologies. The proposed film-fabrication methods are general, facile, environmentally benign, cost-effective, and easy to scale up. The resultant one-step-stripped film was thin (9 ± 1 μm), soft, transparent, and strong, whereas the thickness of the layer-by-layer-cast film was 70 ± 3 μm. FTIR analysis of the films indicated the formation of interactions between the phosphoric groups in sodium phytate and the amino groups in chitosan. More importantly, the water-vapor-permeability values of the one-step-stripped and cast films were 4-5 orders of magnitude lower than chitosan films reported before. Layer-by-layer-cast films in particular exhibited high tensile strength (49.21 ± 1.12 MPa) and were more than three times stronger than other polyelectrolyte multilayer films. Both types of films remained stable in an acidic environment. Furthermore, the layer-by-layer-assembled films presented greater antimicrobial activity than the stripped films. The developed chitosan-sodium phytate films can enhance several biomedical and environmental applications, such as packaging, drug delivery, diagnostics, microfluidics, and biosensing.
追求可持续的功能材料需要开发基于可再生资源和高效制造方法的材料。在这里，我们首先通过一步剥离和层层浇铸技术制备壳聚糖-植酸钠薄膜。所提出的薄膜制造方法具有通用性、简便性、环境友好性、成本效益高和易于放大等优点。所得的一步剥离薄膜很薄（9±1μm），柔软、透明且强度高，而层层浇铸薄膜的厚度为 70±3μm。薄膜的 FTIR 分析表明，植酸钠中的磷酸基团和壳聚糖中的氨基之间形成了相互作用。更重要的是，一步剥离和浇铸薄膜的水蒸气透过率值比以前报道的壳聚糖薄膜低 4-5 个数量级。特别是层层浇铸的薄膜表现出很高的拉伸强度（49.21±1.12MPa），比其他聚电解质多层薄膜强三倍以上。两种类型的薄膜在酸性环境中都很稳定。此外，层层组装的薄膜表现出比剥离的薄膜更高的抗菌活性。所开发的壳聚糖-植酸钠薄膜可以增强许多生物医学和环境应用，如包装、药物输送、诊断、微流控和生物传感。
