Frutos Javier, Andrés Sonia, Trevisi Erminio, Yáñez-Ruiz David R, López Secundino, Santos Alba, Giráldez Francisco Javier
Instituto de Ganadería de Montaña, CSIC-Universidad de León, Finca Marzanas s/n, 24346 Grulleros, León, Spain.
Faculty of Agriculture, Food and Environmental Science, Institute of Zootechnics, Università Cattolica del Sacro Cuore, Via Emilia Parmense 84, 29122 Piacenza, Italy.
Animals (Basel). 2018 May 31;8(6):83. doi: 10.3390/ani8060083.
Early postnatal nutrition may have a significant subsequent impact on metabolic disorders during the entire lifespan of lambs. The aim of the present study was to describe the changes in biochemical, immunological, hepatic, and ruminal parameters of fattening lambs derived from early feed restriction during the suckling phase. Twenty-four merino lambs (average body weight, BW, 4.81 ± 0.256 kg) were used, 12 of them were milk-fed ad libitum (ADL) remaining permanently with their dams, whereas the other 12 lambs (restricted, RES) were subjected to milk restriction. After weaning, all the lambs were fed 35 g/kg BW per day of the same complete pelleted diet to ensure no differences between groups in dry matter intake (603 vs. 607 g/day for ADL and RES lambs, respectively, = 0.703), and were slaughtered at a BW of 27 kg. Biochemical profiles revealed higher concentrations of ceruloplasmin and low-density lipoproteins, whereas insulin concentration was lower in the RES lambs compared to the ADL group. Liver thiobarbituric acid reactive substances were lower in the RES lambs. No significant differences in ruminal or blood immunological parameters were found. In conclusion, early feed restriction promoted metabolic disorders not related to ruminal acidosis occurrence, which can compromise the health status during the fattening period of merino lambs.
出生后早期营养可能会对羔羊整个生命周期中的代谢紊乱产生重大的后续影响。本研究的目的是描述哺乳期早期饲料限制的育肥羔羊在生化、免疫、肝脏和瘤胃参数方面的变化。使用了24只美利奴羔羊（平均体重，BW，4.81±0.256千克），其中12只自由采食牛奶（ADL），一直与母羊在一起，而另外12只羔羊（限制组，RES）则受到牛奶限制。断奶后，所有羔羊每天按体重35克/千克喂食相同的全价颗粒饲料，以确保两组之间干物质摄入量无差异（ADL和RES羔羊分别为603克/天和607克/天，P = 0.703），并在体重达到27千克时屠宰。生化分析显示，RES羔羊中铜蓝蛋白和低密度脂蛋白浓度较高，而胰岛素浓度低于ADL组。RES羔羊肝脏中的硫代巴比妥酸反应物质较低。瘤胃或血液免疫参数未发现显著差异。总之，早期饲料限制会引发与瘤胃酸中毒发生无关的代谢紊乱，这可能会损害美利奴羔羊育肥期的健康状况。
