US Food and Drug Administration, 10903 New Hampshire Ave, Silver Spring, MD, 20993, USA.
Network for Public Health Law, 3701 Wilshire Blvd. #750, Los Angeles, CA, 90010, USA.
Drug Alcohol Depend. 2018 Aug 1;189:37-41. doi: 10.1016/j.drugalcdep.2018.04.020. Epub 2018 May 29.
In response to the ongoing opioid overdose epidemic, many states have enacted laws increasing naloxone access by lay people, such as friends and family members of people who use drugs (PWUD), as well as PWUD themselves.
We utilized Symphony Health Solutions' PHAST Prescription data from 2007 to 2016 to investigate whether naloxone access laws were associated with an increase in naloxone dispensed from retail pharmacies in the United States.
Using a negative binomial regression, we found that naloxone access laws were associated with an average increase of 78 prescriptions dispensed per state per quarter. This represents an average 79% increase in naloxone dispensed from U.S. retail pharmacies, compared with states where there were no such laws.
Our study suggests that naloxone access laws can increase the availability and accessibility of naloxone.
为应对持续的阿片类药物过量流行，许多州已经颁布法律，增加了包括吸毒者（PWUD）朋友和家人在内的非专业人士获取纳洛酮的机会。
我们利用 Symphony Health Solutions 的 PHAST 处方数据（2007 年至 2016 年），调查了纳洛酮获取法是否与美国零售药店纳洛酮配药的增加有关。
通过负二项式回归，我们发现纳洛酮获取法与每个州每季度平均增加 78 份处方有关。这意味着与没有此类法律的州相比，美国零售药店纳洛酮的配药量平均增加了 79%。
我们的研究表明，纳洛酮获取法可以增加纳洛酮的可及性和可获得性。
