州法律授权药剂师开纳洛酮处方与零售药店纳洛酮配药的增加有关。
State laws that authorize pharmacists to prescribe naloxone are associated with increased naloxone dispensing in retail pharmacies.
机构信息
Public Health Strategy and Analysis Staff, Office of Economics and Analysis, Office of Policy, Legislation and International Affairs, Office of the Commissioner, US Food and Drug Administration, USA.
Public Health Strategy and Analysis Staff, Office of Economics and Analysis, Office of Policy, Legislation and International Affairs, Office of the Commissioner, US Food and Drug Administration, USA.
出版信息
Drug Alcohol Depend. 2021 Oct 1;227:109012. doi: 10.1016/j.drugalcdep.2021.109012. Epub 2021 Aug 28.
BACKGROUND
The opioid crisis in the United States continues to worsen. Several states have passed laws granting pharmacists the authority to independently prescribe (not just dispense) naloxone. Since pharmacists are accessible healthcare providers, enhancing their ability to prescribe naloxone, an effective opioid overdose reversal agent, may help combat the ongoing opioid overdose epidemic.
METHOD
Using a nationally representative database on drug dispensing in 2010 to 2018 from Symphony Health, we conducted a cross-sectional study to assess whether state laws authorizing pharmacists to prescribe naloxone were associated with increased naloxone dispensing from retail pharmacies.
RESULTS
The number of naloxone prescriptions dispensed from retail pharmacies increased from 2010 to 2018 and doubled from 2017 to 2018. The presence of state laws authorizing pharmacists to prescribe naloxone is associated with an average increase of 331(95% CI = 43.56, 618.49) prescription dispensed per state per quarter. This represents an approximately 53% increase in naloxone dispensed compared to pharmacies in states where there were no such laws.
CONCLUSIONS
Our study suggests that state laws that allow pharmacists to prescribe and not just dispense naloxone at retail pharmacies can increase the availability and accessibility of naloxone. Adopting and implementing such laws may help reduce serious and life-threatening opioid overdoses.
背景
美国的阿片类药物危机持续恶化。一些州已经通过了赋予药剂师独立开出处方（不仅仅是配药）纳洛酮的权力的法律。由于药剂师是可及的医疗保健提供者，增强他们开出处方纳洛酮（一种有效的阿片类药物过量逆转剂）的能力可能有助于对抗持续的阿片类药物过量流行。
方法
我们使用 Symphony Health 2010 年至 2018 年期间关于药物配药的全国代表性数据库进行了一项横断面研究，以评估授权药剂师开出处方纳洛酮的州法律是否与零售药店纳洛酮配药量的增加有关。
结果
零售药店配出的纳洛酮处方数量从 2010 年到 2018 年增加，并从 2017 年到 2018 年翻了一番。授权药剂师开出处方纳洛酮的州法律的存在与每个州每季度平均增加 331 份（95%CI = 43.56, 618.49）处方有关。这代表与没有此类法律的州的药店相比，纳洛酮的配药量增加了约 53%。
结论
我们的研究表明，允许药剂师在零售药店开出处方而不仅仅是配药的州法律可以增加纳洛酮的可及性和可获得性。采用和实施此类法律可能有助于减少严重和危及生命的阿片类药物过量。
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