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隐匿性莱迪希细胞瘤表现为双侧男性乳腺增生。病例报告及文献综述

Occult Leydig Cell Tumour Presenting as Bilateral Gynaecomastia. Case Report and Literature Review.

作者信息

Patel A B, Wilson L, Rane A

机构信息

Institute of Urology and Nephrology, University College London, UK.

East Surrey Hospital, Redhill, UK.

出版信息

ScientificWorldJournal. 2005 Nov 8;5:884-887. doi: 10.1100/tsw.2005.107. eCollection 2005.

Abstract

Gynaecomastia is the most common benign breast disorder in men. Among the various causes, testicular malignancies are an uncommon, life-threatening condition requiring prompt diagnosis and treatment. The case of a 28-year-old man is discussed, who presented with a 6-month history of painful bilateral gynaecomastia with no abnormality on clinical or biochemical examination. The patient's symptoms spontaneously resolved within 4 weeks. He then represented 10 years later with similar symptoms and an associated secondary hypogonadism. Ultrasound imaging revealed a clinically occult, hypoechoic mass in the left testis (Leydig cell tumour on histology). Clinical and hormonal findings normalized following surgical excision. This report underlines the importance in clinical practice of ultrasonographic evaluation of the testis, in all patients with gynaecomastia, despite unremarkable findings on physical examination.

摘要

男性乳房发育症是男性最常见的良性乳腺疾病。在各种病因中,睾丸恶性肿瘤是一种罕见但危及生命的疾病,需要及时诊断和治疗。本文讨论了一名28岁男性的病例,该患者有6个月的双侧疼痛性男性乳房发育症病史,临床和生化检查均无异常。患者症状在4周内自行缓解。10年后,他再次出现类似症状并伴有继发性性腺功能减退。超声检查发现左侧睾丸有一个临床隐匿的低回声肿块(组织学检查为睾丸间质细胞瘤)。手术切除后,临床和激素检查结果恢复正常。本报告强调,在临床实践中,对于所有男性乳房发育症患者,无论体格检查结果是否明显,对睾丸进行超声评估都很重要。

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