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使用猪进行尾头向撞击致胸腹联合伤的实验研究。

Experimental Study of Thoracoabdominal Injuries Suffered from Caudocephalad Impacts Using Pigs.

作者信息

Guan Sishu, Liao Zhikang, Xiang Hongyi, Zhu Xiyan, Wang Zhong, Zhao Hui, Liu Peng, Lai Xinan

机构信息

Department of Spine Surgery, Daping Hospital, Third Military Medical University, Chongqing 400042, China.

State Key Laboratory of Trauma; Burns & Combined Wound, Institute for Traffic Medicine, Third Military Medical University, Chongqing 400042, China.

出版信息

Appl Bionics Biomech. 2018 May 10;2018:2321053. doi: 10.1155/2018/2321053. eCollection 2018.

DOI:10.1155/2018/2321053
PMID:29861783
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5971294/
Abstract

To know the caudocephalad impact- (CCI-) induced injuries more clearly, 21 adult minipigs, randomly divided into three groups: control group ( = 3), group I ( = 9), and group II ( = 9), were used to perform the CCI experiments on a modified deceleration sled. Configured impact velocity was 0 m/s in the control group, 8 m/s in group I, and 11 m/s in group II. The kinematics and mechanical responses of the subjects were recorded and investigated. The functional change examination and the autopsies were carried out, with which the injuries were evaluated from the Abbreviated Injury Scale (AIS) and the Injury Severity Score (ISS). The subjects in group I and group II experienced the caudocephalad loading at the peak pelvic accelerations of 108.92 ± 58.87 g and 139.13 g ± 78.54 g, with the peak abdomen pressures, 41.24 ± 16.89 kPa and 63.61 ± 65.83 kPa, respectively. The injuries of the spleen, lung, heart, and spine were detected frequently among the tested subjects. The maximal AIS (MAIS) of chest injuries was 4 in group I and 5 in group II, while both the MAIS of abdomen injuries in group I and group II were 5. The ISS in group II was 52.71 ± 6.13, significantly higher than in group I, 26.67 ± 5.02 ( < 0.05). The thoracoabdomen CCI injuries and the mechanical response addressed presently may be useful to conduct both the prevention studies against military or civilian injuries.

摘要

为了更清楚地了解尾头撞击(CCI)所致损伤,将21只成年小型猪随机分为三组:对照组(n = 3)、I组(n = 9)和II组(n = 9),在改良减速雪橇上进行CCI实验。对照组的设定撞击速度为0 m/s,I组为8 m/s,II组为11 m/s。记录并研究了实验对象的运动学和力学反应。进行了功能变化检查和尸检,据此根据简明损伤定级标准(AIS)和损伤严重度评分(ISS)对损伤进行评估。I组和II组的实验对象分别在骨盆峰值加速度为108.92±58.87 g和139.13 g±78.54 g时经历尾头方向的负荷,峰值腹部压力分别为41.24±16.89 kPa和63.61±65.83 kPa。在所测试的实验对象中,脾脏、肺、心脏和脊柱的损伤较为常见。I组胸部损伤的最大AIS为4,II组为5,而I组和II组腹部损伤的最大AIS均为5。II组的ISS为52.71±6.13,显著高于I组的26.67±5.02(P<0.05)。目前所涉及的胸腹CCI损伤和力学反应可能有助于开展针对军事或民用损伤的预防研究。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e80f/5971294/ab31ef1b032d/ABB2018-2321053.008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e80f/5971294/4e431e1d892b/ABB2018-2321053.001.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e80f/5971294/16cf7f141c5a/ABB2018-2321053.007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e80f/5971294/ab31ef1b032d/ABB2018-2321053.008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e80f/5971294/4e431e1d892b/ABB2018-2321053.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e80f/5971294/2b41fccee385/ABB2018-2321053.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e80f/5971294/356832944bc3/ABB2018-2321053.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e80f/5971294/9b09863da719/ABB2018-2321053.004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e80f/5971294/9d1c11d47d38/ABB2018-2321053.005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e80f/5971294/49159d2c1bc5/ABB2018-2321053.006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e80f/5971294/16cf7f141c5a/ABB2018-2321053.007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e80f/5971294/ab31ef1b032d/ABB2018-2321053.008.jpg

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