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蝶腭神经节阻滞治疗急性偏头痛

Sphenopalatine Ganglion Block for the Treatment of Acute Migraine Headache.

作者信息

Binfalah Mohamed, Alghawi Eman, Shosha Eslam, Alhilly Ali, Bakhiet Moiz

机构信息

University Medical Center, King Abdullah Medical City, P.O. Box 26671, Adliya, Bahrain.

Ministry of Health, Building 1228, Road 4025, 340 Juffair, Bahrain.

出版信息

Pain Res Treat. 2018 May 7;2018:2516953. doi: 10.1155/2018/2516953. eCollection 2018.

DOI:10.1155/2018/2516953
PMID:29862074
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5971252/
Abstract

Transnasal sphenopalatine ganglion block is emerging as is an attractive and effective treatment modality for acute migraine headaches, cluster headache, trigeminal neuralgia, and several other conditions. We assessed the efficacy and safety of this treatment using the Sphenocath® device. 55 patients with acute migraine headaches underwent this procedure, receiving 2 ml of 2% lidocaine in each nostril. Pain numeric rating scale (baseline, 15 minutes, 2 hours, and 24 hours) and patient global impression of change (2 hours and 24 hours after treatment) were recorded. The majority of patients became headache-free at 15 minutes, 2 hours, and 24 hours after procedure (70.9%, 78.2%, and 70.4%, resp.). The rate of headache relief (50% or more reduction in headache intensity) was 27.3% at 15 minutes, 20% at 2 hours, and 22.2% at 24 hours. The mean pain numeric rating scale decreased significantly at 15 minutes, 2 hours, and 24 hours, respectively. Most patients rated the results as very good or good. The procedure was well-tolerated with few adverse events. This treatment is emerging as an effective and safe option for management of acute migraine attacks.

摘要

经鼻蝶腭神经节阻滞正逐渐成为一种治疗急性偏头痛、丛集性头痛、三叉神经痛及其他几种病症的有吸引力且有效的治疗方式。我们使用Sphenocath®设备评估了这种治疗的疗效和安全性。55例急性偏头痛患者接受了该治疗,每个鼻孔注射2毫升2%利多卡因。记录疼痛数字评分量表(基线、15分钟、2小时和24小时)以及患者对变化的整体印象(治疗后2小时和24小时)。大多数患者在治疗后15分钟、2小时和24小时时头痛消失(分别为70.9%、78.2%和70.4%)。头痛缓解率(头痛强度降低50%或更多)在15分钟时为27.3%,2小时时为20%,24小时时为22.2%。疼痛数字评分量表的平均值在15分钟、2小时和24小时时分别显著降低。大多数患者对结果的评价为非常好或好。该治疗耐受性良好,不良事件较少。这种治疗正逐渐成为管理急性偏头痛发作的一种有效且安全的选择。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7462/5971252/d1fd6557e6d9/PRT2018-2516953.006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7462/5971252/2e3f7f547427/PRT2018-2516953.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7462/5971252/4300af02a983/PRT2018-2516953.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7462/5971252/99700dcf5970/PRT2018-2516953.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7462/5971252/40f9a8b9324a/PRT2018-2516953.004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7462/5971252/bf8ed4eb931d/PRT2018-2516953.005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7462/5971252/d1fd6557e6d9/PRT2018-2516953.006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7462/5971252/2e3f7f547427/PRT2018-2516953.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7462/5971252/4300af02a983/PRT2018-2516953.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7462/5971252/99700dcf5970/PRT2018-2516953.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7462/5971252/40f9a8b9324a/PRT2018-2516953.004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7462/5971252/bf8ed4eb931d/PRT2018-2516953.005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7462/5971252/d1fd6557e6d9/PRT2018-2516953.006.jpg

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