上转换纳米晶“装甲”硅光纤具有优异的光致发光性能，可用于 miRNA 检测。
Upconversion nanocrystal 'armoured' silica fibres with superior photoluminescence for miRNA detection.
机构信息
State Key Laboratory of Silicon Materials, School of Materials Science and Engineering, Zhejiang University, Hangzhou, Zhejiang 310027, People's Republic of China.
出版信息
Chem Commun (Camb). 2018 Jun 14;54(49):6324-6327. doi: 10.1039/c8cc03480j.
PMID:29862401
Abstract
We have fabricated a flexible membrane, consisting of SiO2 nanofibres armoured with upconversion nanoparticles, exhibiting intense photoluminescence. These assemblies were subsequently grafted with molecular beacons to produce a biosensor suitable for the detection of specific microRNA and with applications in early cancer detection and point-of-care diagnosis.
摘要
我们制备了一种由上转换纳米粒子包覆的二氧化硅纳米纤维组成的柔性膜，该膜表现出强烈的光致发光。随后，这些组装体被分子信标接枝，产生了一种适用于特定 microRNA 检测的生物传感器，并可应用于早期癌症检测和即时诊断。
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