Wang Ling, Yarosz Shannon, Aghamoosa Hosain, Grinspan Zachary, Patel Anup D
1 Data Resource Center, Nationwide Children's Hospital, Columbus, OH, USA.
2 Division of Pediatric Neurology, Department of Pediatrics, Nationwide Children's Hospital, Columbus, OH, USA.
J Child Neurol. 2018 Sep;33(10):639-641. doi: 10.1177/0883073818774960. Epub 2018 Jun 4.
An infantile spasm is a brief seizure type that is characteristic of West syndrome. Many infants present with infantile spasms between 3-12 months of age. Early diagnosis and proper treatment of patients with infantile spasms can lead to improved clinical outcomes. However, proper identification of these patients using claims data with validation has not been performed. The authors developed and tested several algorithms using claims data. Claims data consisted of using International Classification of Disease (ICD), Current Procedural Terminology (CPT), and prescription codes. Access to the claims database was from an accountable care organization. The algorithm using the specific ICD code for infantile spasms only performed the best with high sensitivity and specificity. This algorithm can be used to perform additional research in claims data for patients with infantile spasms.
婴儿痉挛是一种短暂的癫痫发作类型，是韦斯特综合征的特征。许多婴儿在3至12个月大时出现婴儿痉挛。对婴儿痉挛患者进行早期诊断和适当治疗可改善临床结局。然而，尚未使用经过验证的索赔数据对这些患者进行正确识别。作者使用索赔数据开发并测试了几种算法。索赔数据包括使用国际疾病分类（ICD）、现行程序术语（CPT）和处方代码。索赔数据库来自一个责任医疗组织。仅使用婴儿痉挛特定ICD代码的算法在高灵敏度和特异性方面表现最佳。该算法可用于对婴儿痉挛患者的索赔数据进行进一步研究。
