Ye L, Wang Z, Li Z, Lv C, Man M-Q
Dalian Skin Disease Hospital, Dalian, Liaoning, China.
Department of Dermatology, The 7th People's Hospital of Shenyang City, Shenyang, Liaoning, China.
Skin Res Technol. 2019 Jan;25(1):25-29. doi: 10.1111/srt.12590. Epub 2018 Jun 4.
Measurements of transepidermal water loss (TEWL) and stratum corneum (SC) hydration are important for assessing epidermal functions. However, the availability of reliable and user-friendly devices, which can simultaneously measure both TEWL and SC hydration and can allow health providers to remotely access data in time, is limited.
GPSkin Barrier was compared with MPA5 system in the measurements of TEWL and SC hydration on the cheek, the dorsal hand, and the forearm in 200 normal volunteers, including 126 females and 74 males, aged 1-78 years with an average age of 45.24 ± 1.04 years. Correlation of data measured with MPA5 system and GPSkin Barrier was determined.
Levels of both TEWL and SC hydration measured with the Barrie GPSkin Barrier were lower than that with MPA5 system on all 3 body sites except for hydration on the cheek. The levels of both TEWL and SC hydration measured with GpSkin Barrier were correlated well with that measured with MPA5 system on all 3 body sites CONCLUSIONS: GPSkin Barrier is a reliable, affordable, and versatile device for assessing epidermal permeability barrier function and SC hydration.
经表皮水分流失（TEWL）和角质层（SC）水合作用的测量对于评估表皮功能很重要。然而，能够同时测量TEWL和SC水合作用，并能让医疗服务提供者及时远程获取数据的可靠且用户友好型设备有限。
在200名正常志愿者（包括126名女性和74名男性，年龄1至78岁，平均年龄45.24±1.04岁）的脸颊、手背和前臂上，对GPSkin Barrier与MPA5系统在TEWL和SC水合作用测量方面进行了比较。确定了MPA5系统和GPSkin Barrier所测数据的相关性。
除脸颊的水合作用外，在所有3个身体部位，用Barrie GPSkin Barrier测量的TEWL和SC水合作用水平均低于MPA5系统。在所有3个身体部位，用GpSkin Barrier测量的TEWL和SC水合作用水平与用MPA5系统测量的结果相关性良好。结论：GPSkin Barrier是一种用于评估表皮渗透屏障功能和SC水合作用的可靠、经济且多功能的设备。
