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造血干细胞移植背景下的用药错误:系统评价。

Medication Errors in the Context of Hematopoietic Stem Cell Transplantation: A Systematic Review.

机构信息

Author Affiliations: Instituto Nacional de Câncer (Mss Lermontov and Brasil) and Universidade Federal Fluminense (Ms Carvalho), Rio de Janeiro, Brazil.

出版信息

Cancer Nurs. 2019 Sep/Oct;42(5):365-372. doi: 10.1097/NCC.0000000000000613.

DOI:10.1097/NCC.0000000000000613
PMID:29863578
Abstract

BACKGROUND

There have been numerous efforts by health institutions and professionals to prevent and reduce medication errors.

OBJECTIVES

The aim of this study was to identify in the literature the incidence, related factors, consequences, and prevention mechanisms of medication errors in the context of hematopoietic stem cell transplantation.

METHODS

This is a systematic review carried out in the databases LILACS, PubMed, PMC, EMBASE, and CINAHL databases, from January 11 to 13, 2017.

RESULTS

Eleven studies were included in this review and presented in 4 categories of analysis. (1) occurrence-most of the medication errors were related to administration and prescription; (2) related factors-multicausal, highlighting issues including polypharmacy, lack of double checking, and similarity between the medications' names; (3) consequences-the main ones were associated with adverse reactions, with prolonged hospitalization time as outcome; (4) preventive measures-related to safe practices in pharmacotherapy, such as double check and application of the 10 rights of medication administration.

CONCLUSION

Medication administration is an activity of great responsibility for nursing; however, in order to achieve a decrease in medication errors, prevention strategies are necessary for the whole health team.

IMPLICATIONS FOR PRACTICE

Practice improvements are needed including establishing institutional drug administration protocols and keeping them updated, using a computerized prescription system, and promoting patient safety with staff.

摘要

背景

医疗机构和专业人员已经做出了许多努力,以预防和减少用药错误。

目的

本研究旨在确定造血干细胞移植背景下用药错误的发生率、相关因素、后果和预防机制。

方法

这是一项于 2017 年 1 月 11 日至 13 日在 LILACS、PubMed、PMC、EMBASE 和 CINAHL 数据库中进行的系统评价。

结果

本综述纳入了 11 项研究,并分为 4 类进行分析。(1)发生情况——大多数用药错误与给药和处方有关;(2)相关因素——多因素,突出了包括多种药物、缺乏双重检查以及药物名称相似等问题;(3)后果——主要与不良反应有关,以延长住院时间为结果;(4)预防措施——与药物治疗的安全实践有关,如双重检查和应用给药的 10 项权利。

结论

给药是护理工作的一项重要责任活动;但是,为了减少用药错误,整个医疗团队都需要采取预防策略。

实践意义

需要改进实践,包括制定机构用药管理方案并及时更新、使用计算机化处方系统以及通过员工促进患者安全。

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引用本文的文献

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How to get over with medication errors underestimation? Improving indices of medication errors with focus on intravenous medications in hematopoietic stem cell transplantation setting; a direct observation study.如何克服对用药错误低估的问题?在造血干细胞移植环境下,通过关注静脉药物来提高用药错误指标:一项直接观察研究。
PLoS One. 2024 Aug 22;19(8):e0307753. doi: 10.1371/journal.pone.0307753. eCollection 2024.