Claoue C, Hodges T, Hill T, Blyth W, Easty D
Department of Ophthalmology, University of Bristol, Medical School, UK.
Br J Exp Pathol. 1987 Aug;68(4):585-93.
A murine model of zosteriform spread of herpes simplex virus to the eye is reported. Viral antigens were demonstrated by a peroxidase-antiperoxidase technique in the trigeminal ganglion, iris, ciliary body, and cornea. The histology suggested a spontaneous bacterial superinfection during the later stages of the herpetic disease of the cornea. The relevance to human disease is discussed.
报道了单纯疱疹病毒向眼部带状扩散的小鼠模型。通过过氧化物酶-抗过氧化物酶技术在三叉神经节、虹膜、睫状体和角膜中证实了病毒抗原。组织学检查提示在角膜疱疹疾病后期存在自发性细菌二重感染。并讨论了其与人类疾病的相关性。
