Hyperlipidemia in Stroke Pathobiology and Therapy: Insights and Perspectives.
作者信息
Menet Romain, Bernard Maxime, ElAli Ayman
机构信息
Neuroscience Axis, CHU de Québec Research Center (CHUL), Québec City, QC, Canada.
Department of Psychiatry and Neuroscience, Faculty of Medicine, Laval University, Québec City, QC, Canada.
出版信息
Front Physiol. 2018 May 15;9:488. doi: 10.3389/fphys.2018.00488. eCollection 2018.
Abstract
摘要
相似文献
1
Hyperlipidemia in Stroke Pathobiology and Therapy: Insights and Perspectives.《高脂血症在卒中病理生物学与治疗中的见解与展望》
Front Physiol. 2018 May 15;9:488. doi: 10.3389/fphys.2018.00488. eCollection 2018.
2
Astrocytes, therapeutic targets for neuroprotection and neurorestoration in ischemic stroke.星形胶质细胞，缺血性脑卒中神经保护和神经修复的治疗靶点。
Prog Neurobiol. 2016 Sep;144:103-20. doi: 10.1016/j.pneurobio.2015.09.008. Epub 2015 Oct 9.
3
Influences of hyperlipidemia history on stroke outcome; a retrospective cohort study based on the Kyoto Stroke Registry.高脂血症病史对卒中结局的影响；一项基于京都卒中登记处的回顾性队列研究。
BMC Neurol. 2015 Mar 25;15:44. doi: 10.1186/s12883-015-0297-1.
4
The Role of Monocytes in Ischemic Stroke Pathobiology: New Avenues to Explore.单核细胞在缺血性脑卒中病理生物学中的作用：有待探索的新途径。
Front Aging Neurosci. 2016 Feb 22;8:29. doi: 10.3389/fnagi.2016.00029. eCollection 2016.
5
Hyperlipidemia attenuates vascular endothelial growth factor-induced angiogenesis, impairs cerebral blood flow, and disturbs stroke recovery via decreased pericyte coverage of brain endothelial cells.高脂血症通过减少脑内皮细胞周细胞对血管内皮生长因子诱导的血管生成的覆盖，损害脑血流，并干扰中风恢复。
Arterioscler Thromb Vasc Biol. 2013 Jul;33(7):1561-7. doi: 10.1161/ATVBAHA.112.300749. Epub 2013 Apr 4.
6
Rate and adequacy of cholesterol screening in patients admitted to a large rehabilitation unit after stroke.中风后入住大型康复单元患者的胆固醇筛查率及充分性。
Arch Phys Med Rehabil. 2005 Jan;86(1):69-72. doi: 10.1016/j.apmr.2003.12.034.
7
Potential Immunotherapeutic Targets on Myeloid Cells for Neurovascular Repair After Ischemic Stroke.缺血性中风后神经血管修复中髓样细胞上的潜在免疫治疗靶点
Front Neurosci. 2019 Aug 9;13:758. doi: 10.3389/fnins.2019.00758. eCollection 2019.
8
Systems Biology of Immunomodulation for Post-Stroke Neuroplasticity: Multimodal Implications of Pharmacotherapy and Neurorehabilitation.中风后神经可塑性免疫调节的系统生物学：药物治疗和神经康复的多模态影响
Front Neurol. 2016 Jun 28;7:94. doi: 10.3389/fneur.2016.00094. eCollection 2016.
9
Mechanisms and challenges in translational stroke research.转化性中风研究中的机制与挑战。
J Investig Med. 2016 Apr;64(4):827-9. doi: 10.1136/jim-2016-000104.
10
Challenges of neuroprotection and neurorestoration in ischemic stroke treatment.缺血性中风治疗中神经保护与神经修复面临的挑战。
Cerebrovasc Dis. 2005;20 Suppl 2:148-58. doi: 10.1159/000089369. Epub 2005 Dec 2.
引用本文的文献
1
Novel carboxamide derivatives increase lipoprotein lipase gene expression in endothelial and adipose tissues of triton WR- 1339 induced hyperlipidemic rats.新型羧酰胺衍生物可增加 Triton WR - 1339 诱导的高脂血症大鼠内皮组织和脂肪组织中脂蛋白脂肪酶基因的表达。
Naunyn Schmiedebergs Arch Pharmacol. 2025 Apr 26. doi: 10.1007/s00210-025-04174-z.
2
TRPM2 overactivation drives hyperlipidemia-induced dysfunction of myeloid cells and neurovascular units.瞬时受体电位阳离子通道亚家族M成员2（TRPM2）过度激活会导致高脂血症诱导的髓样细胞和神经血管单元功能障碍。
Cell Rep Med. 2025 Mar 18;6(3):101998. doi: 10.1016/j.xcrm.2025.101998. Epub 2025 Mar 7.
3
Association between composite dietary antioxidant index and hyperlipidemia in adults based on the NHANES.基于美国国家健康与营养检查调查（NHANES）的成人复合膳食抗氧化指数与高脂血症之间的关联。
Sci Rep. 2025 Jan 18;15(1):2382. doi: 10.1038/s41598-025-86223-4.
4
Prognostic Value of Fibrosis-4 in Acute Ischemic Stroke Patients Undergoing Intravenous Thrombolysis.纤维蛋白原-4 在接受静脉溶栓治疗的急性缺血性脑卒中患者中的预后价值。
Clin Interv Aging. 2024 Oct 7;19:1663-1674. doi: 10.2147/CIA.S469899. eCollection 2024.
5
A Retrospective Analysis of the Underlying Health Status of Patients Treated for Stroke in the Emergency Department of a Community Hospital Situated in a Health Professional Shortage Area.对位于医疗专业人员短缺地区的一家社区医院急诊科接受中风治疗的患者基础健康状况的回顾性分析。
Cureus. 2024 Aug 29;16(8):e68150. doi: 10.7759/cureus.68150. eCollection 2024 Aug.
6
A case report about anorexia nervosa and ischemic stroke: what can we learn?一例神经性厌食症与缺血性中风的病例报告：我们能学到什么？
J Eat Disord. 2024 Aug 6;12(1):111. doi: 10.1186/s40337-024-01074-0.
7
Neuron-specific enolase as a prognostic biomarker in acute ischemic stroke patients treated with reperfusion therapies.神经元特异性烯醇化酶作为接受再灌注治疗的急性缺血性脑卒中患者的预后生物标志物。
Front Neurol. 2024 Jul 18;15:1408111. doi: 10.3389/fneur.2024.1408111. eCollection 2024.
8
Nutritional roles and therapeutic potentials of dietary sphingomyelin in brain diseases.膳食鞘磷脂在脑部疾病中的营养作用及治疗潜力
J Clin Biochem Nutr. 2024 May;74(3):185-191. doi: 10.3164/jcbn.23-97. Epub 2023 Dec 26.
9
Dyslipidemia versus obesity as predictors of ischemic stroke prognosis: a multi-center study in China.血脂异常与肥胖作为缺血性脑卒中预后的预测因素：中国多中心研究。
Lipids Health Dis. 2024 Mar 9;23(1):72. doi: 10.1186/s12944-024-02061-9.
10
A Parametric Time-to-Event Modelling of Recurrent Ischemic Stroke After Index Stroke Among Patients With and Without Diabetes Mellitus: Implementation of Temporal Validation of the Model.糖尿病患者和非糖尿病患者首次中风后复发性缺血性中风的参数生存时间建模：模型时间验证的实施
Cureus. 2023 Dec 19;15(12):e50794. doi: 10.7759/cureus.50794. eCollection 2023 Dec.
本文引用的文献
1
Differences in risk factors for 3 types of stroke: UK prospective study and meta-analyses.3 种类型中风的危险因素差异：英国前瞻性研究和荟萃分析。
Neurology. 2018 Jan 23;90(4):e298-e306. doi: 10.1212/WNL.0000000000004856. Epub 2018 Jan 10.
2
The impact of hyperglycemia and hyperlipidemia on plasma P-selectin and platelet markers after ischemic stroke.缺血性中风后高血糖和高脂血症对血浆P-选择素及血小板标志物的影响。
Arch Med Sci. 2017 Aug;13(5):1049-1056. doi: 10.5114/aoms.2017.65816. Epub 2017 Feb 1.
3
Vascular Endothelial Growth Factor Isoform-B Stimulates Neurovascular Repair After Ischemic Stroke by Promoting the Function of Pericytes via Vascular Endothelial Growth Factor Receptor-1.血管内皮生长因子异构体-B 通过血管内皮生长因子受体-1 促进周细胞的功能来刺激缺血性中风后的神经血管修复。
Mol Neurobiol. 2018 May;55(5):3611-3626. doi: 10.1007/s12035-017-0478-6. Epub 2017 Mar 14.
4
Low Density Lipoprotein Cholesterol and the Outcome of Acute Ischemic Stroke: Results of a Large Hospital-Based Study.低密度脂蛋白胆固醇与急性缺血性卒中的结局：一项基于大型医院的研究结果
Eur Neurol. 2016;76(5-6):195-201. doi: 10.1159/000450604. Epub 2016 Oct 6.
5
Hyperlipidemia is associated with lower risk of poststroke mortality independent of statin use: A population-based study.高脂血症与卒中后死亡率较低相关，与他汀类药物使用无关：一项基于人群的研究。
Int J Stroke. 2017 Feb;12(2):152-160. doi: 10.1177/1747493016670175. Epub 2016 Sep 24.
6
Prolonged diet-induced obesity in mice modifies the inflammatory response and leads to worse outcome after stroke.长期饮食诱导的小鼠肥胖会改变炎症反应，并导致中风后预后更差。
J Neuroinflammation. 2015 Aug 4;12:140. doi: 10.1186/s12974-015-0359-8.
7
Hyperlipidemia exacerbates cerebral injury through oxidative stress, inflammation and neuronal apoptosis in MCAO/reperfusion rats.高脂血症通过氧化应激、炎症和神经元凋亡加重大脑中动脉闭塞/再灌注大鼠的脑损伤。
Exp Brain Res. 2015 Oct;233(10):2753-65. doi: 10.1007/s00221-015-4269-x. Epub 2015 Aug 4.
8
The many roles of statins in ischemic stroke.他汀类药物在缺血性卒中中的多种作用。
Curr Neuropharmacol. 2014 Dec;12(6):564-74. doi: 10.2174/1570159X12666140923210929.
9
Influences of hyperlipidemia history on stroke outcome; a retrospective cohort study based on the Kyoto Stroke Registry.高脂血症病史对卒中结局的影响；一项基于京都卒中登记处的回顾性队列研究。
BMC Neurol. 2015 Mar 25;15:44. doi: 10.1186/s12883-015-0297-1.
10
Pre and Post-stroke Use of Statins Improves Stroke Outcome.中风前后使用他汀类药物可改善中风预后。
Indian J Community Med. 2014 Oct;39(4):214-7. doi: 10.4103/0970-0218.143021.
Zotero 插件