用于光声成像的 NIR 吸收噻吩基姜黄素对比剂的表征。
Characterization of a NIR absorbing thienyl curcumin contrast agent for photoacoustic imaging.
机构信息
Department of Chemistry, University of Massachusetts Boston, 100 Morrissey Boulevard, Boston, Massachusetts 02125, USA.
出版信息
Chem Commun (Camb). 2018 Jun 14;54(49):6352-6355. doi: 10.1039/c8cc03727b.
Abstract
The synthesis and characterization of a bis(2-dimethylaminothien-5-yl)curcumin boron difluoride chromophore is presented. Photophysical, electrochemical and computational investigations establish the properties of its absorption in the Vis-NIR spectral range relative to established curcumin dyes. Application of this thienyl curcumin dye as a photoacoustic contrast agent is investigated against the dicarbocyanine Cy5 dye in the 675-735 nm excitation range.
摘要
本文介绍了一种双（2-二甲氨基噻吩-5-基）姜黄素硼酸二氟络合物的合成与表征。光物理、电化学和计算研究确立了其在可见-近红外光谱范围内吸收的性质，与已建立的姜黄素染料相对比。在 675-735nm 激发范围内，将这种噻吩基姜黄素染料作为光声对比剂进行了研究，与二碳菁染料 Cy5 进行了对比。
相似文献
1
Characterization of a NIR absorbing thienyl curcumin contrast agent for photoacoustic imaging.用于光声成像的 NIR 吸收噻吩基姜黄素对比剂的表征。
Chem Commun (Camb). 2018 Jun 14;54(49):6352-6355. doi: 10.1039/c8cc03727b.
2
Photophysical and Photoacoustic Properties of π-Extended Curcumin Dyes. Effects of the Terminal Dimethylamino Electron-donor and the Bridging Aryl Ring.π-扩展姜黄素染料的光物理和光声性质。末端二甲氨基给电子和桥连芳环的影响。
Photochem Photobiol. 2019 Jan;95(1):280-292. doi: 10.1111/php.12980. Epub 2018 Aug 17.
3
Characterization of Triphenylamine and Ferrocenyl Donor-π-donor Vinyl BODIPY Derivatives as Photoacoustic Contrast Agents.三苯胺和二茂铁基供体-π-供体乙烯基BODIPY衍生物作为光声造影剂的表征
Photochem Photobiol. 2022 Jan;98(1):62-72. doi: 10.1111/php.13427. Epub 2021 Apr 20.
4
Electronic Characterization of Vis-NIR Absorbing Noninnocent Ruthenium Oxyquinolate-merocyanine Complexes and their Photoacoustic Emission in Aqueous Micellar Solution.可见-近红外吸收型非无辜钌氧喹啉-部花青配合物的电子表征及其在胶束水溶液中的光声发射
Photochem Photobiol. 2023 Mar;99(2):547-561. doi: 10.1111/php.13715. Epub 2022 Oct 17.
5
A Dual-Mode Near-Infrared Optical and Photoacoustic Imaging Agent Based on a Low Energy Absorbing Ytterbium Complex.一种基于低能量吸收镱配合物的双模式近红外光学与光声成像剂。
J Am Chem Soc. 2024 May 15;146(19):12913-12918. doi: 10.1021/jacs.4c03406. Epub 2024 May 3.
6
Photophysical and Photoacoustic Properties of Quadrupolar Borondifluoride Curcuminoid Dyes.四极硼二氟姜黄素类染料的光物理和光声性质
Chemistry. 2018 Jan 19;24(4):906-917. doi: 10.1002/chem.201704423. Epub 2017 Dec 14.
7
Near-Infrared Squaraine Dye Encapsulated Micelles for in Vivo Fluorescence and Photoacoustic Bimodal Imaging.近红外方酸染料包封胶束用于体内荧光和光声双模成像。
ACS Nano. 2015 Jun 23;9(6):5695-704. doi: 10.1021/acsnano.5b02172. Epub 2015 Jun 2.
8
Boron Difluoride Curcuminoid Fluorophores with Enhanced Two-Photon Excited Fluorescence Emission and Versatile Living-Cell Imaging Properties.具有增强的双光子激发荧光发射和多功能活细胞成像特性的二氟化硼姜黄素类荧光团。
Chemistry. 2016 Apr 4;22(15):5219-32. doi: 10.1002/chem.201504903. Epub 2016 Feb 25.
9
Effect of substitution on the excited state photophysical and spectral properties of boron difluoride curcumin complex dye and their derivatives: A time dependent-DFT study.硼二氟代姜黄素配合物染料及其衍生物取代基对激发态光物理和光谱性质的影响：含时密度泛函理论研究。
J Photochem Photobiol B. 2019 Oct;199:111595. doi: 10.1016/j.jphotobiol.2019.111595. Epub 2019 Aug 22.
10
Synthesis, Characterization, and Biomedical Applications of a Targeted Dual-Modal Near-Infrared-II Fluorescence and Photoacoustic Imaging Nanoprobe.靶向双模态近红外-II 荧光和光声成像纳米探针的合成、表征及生物医学应用。
ACS Nano. 2017 Dec 26;11(12):12276-12291. doi: 10.1021/acsnano.7b05966. Epub 2017 Dec 11.
引用本文的文献
1
Characterization of Triphenylamine and Ferrocenyl Donor-π-donor Vinyl BODIPY Derivatives as Photoacoustic Contrast Agents.三苯胺和二茂铁基供体-π-供体乙烯基BODIPY衍生物作为光声造影剂的表征
Photochem Photobiol. 2022 Jan;98(1):62-72. doi: 10.1111/php.13427. Epub 2021 Apr 20.
2
Photoacoustic Imaging Probes Based on Tetrapyrroles and Related Compounds.基于四吡咯及其相关化合物的光声成像探针。
Int J Mol Sci. 2020 Apr 27;21(9):3082. doi: 10.3390/ijms21093082.
3
Photophysical and Photoacoustic Properties of π-Extended Curcumin Dyes. Effects of the Terminal Dimethylamino Electron-donor and the Bridging Aryl Ring.π-扩展姜黄素染料的光物理和光声性质。末端二甲氨基给电子和桥连芳环的影响。
Photochem Photobiol. 2019 Jan;95(1):280-292. doi: 10.1111/php.12980. Epub 2018 Aug 17.
本文引用的文献
1
An aza-BODIPY photosensitizer for photoacoustic and photothermal imaging guided dual modal cancer phototherapy.一种用于光声和光热成像引导的双模态癌症光疗的氮杂硼二吡咯光敏剂。
J Mater Chem B. 2017 Feb 28;5(8):1566-1573. doi: 10.1039/c6tb02979e. Epub 2017 Feb 3.
2
Conformational Restrictions in meso-(2-Thiazolyl)-BODIPYs: Large Stokes Shift and pH-Dependent Optical Properties.内消旋-(2-噻唑基)-BODIPY的构象限制：大斯托克斯位移和pH依赖性光学性质
Chempluschem. 2016 Sep;81(9):955-963. doi: 10.1002/cplu.201600254. Epub 2016 Jul 12.
3
Photophysical and Photoacoustic Properties of Quadrupolar Borondifluoride Curcuminoid Dyes.四极硼二氟姜黄素类染料的光物理和光声性质
Chemistry. 2018 Jan 19;24(4):906-917. doi: 10.1002/chem.201704423. Epub 2017 Dec 14.
4
Push-pull type meso-ester substituted BODIPY near-infrared dyes as contrast agents for photoacoustic imaging.推挽型中酯取代的BODIPY近红外染料作为光声成像的造影剂。
Org Biomol Chem. 2017 May 31;15(21):4531-4535. doi: 10.1039/c7ob00965h.
5
Carbazole-Linked Near-Infrared Aza-BODIPY Dyes as Triplet Sensitizers and Photoacoustic Contrast Agents for Deep-Tissue Imaging.咔唑连接的近红外氮杂硼二吡咯染料作为用于深层组织成像的三线态敏化剂和光声造影剂
Chemistry. 2017 May 11;23(27):6570-6578. doi: 10.1002/chem.201605702. Epub 2017 Apr 18.
6
Emerging Designs of Activatable Photoacoustic Probes for Molecular Imaging.用于分子成像的可激活光声探针的新兴设计
Bioconjug Chem. 2016 Dec 21;27(12):2808-2823. doi: 10.1021/acs.bioconjchem.6b00641. Epub 2016 Dec 8.
7
Self-quenched semiconducting polymer nanoparticles for amplified in vivo photoacoustic imaging.用于放大体内光声成像的自猝灭半导体聚合物纳米粒子。
Biomaterials. 2017 Mar;119:1-8. doi: 10.1016/j.biomaterials.2016.12.004. Epub 2016 Dec 8.
8
Recent Advances in Photoacoustic Imaging for Deep-Tissue Biomedical Applications.用于深层组织生物医学应用的光声成像最新进展
Theranostics. 2016 Oct 7;6(13):2394-2413. doi: 10.7150/thno.16715. eCollection 2016.
9
Naphthalene-fused BODIPY near-infrared dye as a stable contrast agent for in vivo photoacoustic imaging.萘并硼二吡咯近红外染料作为用于体内光声成像的稳定造影剂。
Chem Commun (Camb). 2016 Sep 20;52(77):11504-11507. doi: 10.1039/c6cc05126j.
10
Exceptional Single-Molecule Transport Properties of Ladder-Type Heteroacene Molecular Wires.梯型杂环并苯分子线的单分子输运性质的异常现象
J Am Chem Soc. 2016 Aug 24;138(33):10630-5. doi: 10.1021/jacs.6b05983. Epub 2016 Aug 16.
Zotero 插件