核孔复合体：全球保守与局部变异。
Nuclear Pore Complexes: Global Conservation and Local Variation.
机构信息
Institute of Biochemistry and Molecular Cell Biology, Medical School, RWTH Aachen University, 52074 Aachen, Germany.
Institute of Biochemistry and Molecular Cell Biology, Medical School, RWTH Aachen University, 52074 Aachen, Germany.
出版信息
Curr Biol. 2018 Jun 4;28(11):R674-R677. doi: 10.1016/j.cub.2018.04.032.
PMID:29870710
Abstract
Nuclear pore complexes are the transport gates to the nucleus. Most proteins forming these huge complexes are evolutionarily conserved, as is the eightfold symmetry of these complexes. A new study reporting the structure of the yeast nuclear pore complex now shows striking differences from its human counterpart.
摘要
核孔复合体是细胞核的运输门户。形成这些巨大复合物的大多数蛋白质在进化上是保守的，这些复合物的八重对称性也是如此。一项新的研究报告了酵母核孔复合体的结构，现在显示出与人类核孔复合体的惊人差异。
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