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年轻患者憩室炎的手术治疗效果:来自 NSQIP 数据库的结果。

Surgical outcomes for diverticulitis in young patients: results from the NSQIP database.

机构信息

Department of Colorectal Surgery, Digestive Disease Institute, Cleveland Clinic, 9500 Euclid Ave., Cleveland, OH, 44195, USA.

出版信息

Surg Endosc. 2018 Dec;32(12):4953-4956. doi: 10.1007/s00464-018-6256-3. Epub 2018 Jun 5.

Abstract

BACKGROUND

The incidence of diverticulitis is increasing among young patients (≤ 50 years), as are rates of recurrent disease. There is ongoing controversy regarding the best management strategy for this patient group. Guidelines have changed from elective colectomy after a single episode to a more individualized approach no longer based on patient age. This study investigated the clinical presentation and surgical outcomes of young patients undergoing surgery for diverticulitis over two time periods.

METHODS

The American College of Surgeons National Surgical Quality Improvement Program database was searched from 2005 to 2014 to identify all patients ≤ 50 with a diagnosis of diverticulitis. Data were obtained on patient demographics, comorbidity, perioperative details, and 30-day post-operative outcomes. Data were compared between two time periods, being 2005-2010 (Group 1) and 2011-2014 (Group 2).

RESULTS

10,844 patients were included in the analysis. The mean patient age was 43 years (range 18-50), and 35% were female. Significantly more patients were obese (BMI > 30) in Group 2 (52%) versus Group 1 (47%). Laparoscopic surgery and emergency surgery and perforation rates were significantly higher in Group 2. Wound infection was significantly less in Group 2. Post-operative organ/space infection and medical morbidity were significantly higher in Group 2.

CONCLUSIONS

In recent years, there has been a change to a more conservative approach for elective colonic resection in young patients with a history of diverticulitis. Increasingly young patients presenting for surgery for diverticulitis are male and obese, and increased rates of post-operative medical morbidity have been observed. The laparoscopic approach is more common, with resultant increased operative times, and decreased wound infection rates. The observed increased in emergency surgery and perforation rates may be explained by the change in management approach with less elective resections.

摘要

背景

憩室炎在年轻患者(≤ 50 岁)中的发病率正在增加,疾病的复发率也在增加。对于这组患者,最佳治疗策略仍存在争议。指南已从单次发作后的选择性结肠切除术转变为不再基于患者年龄的更个体化的方法。本研究调查了两个时期接受憩室炎手术的年轻患者的临床表现和手术结果。

方法

从 2005 年到 2014 年,美国外科医师学会国家外科质量改进计划数据库被检索,以确定所有诊断为憩室炎且年龄≤50 岁的患者。收集患者人口统计学、合并症、围手术期详细信息和 30 天术后结果的数据。将数据在两个时期进行比较,分别是 2005-2010 年(第 1 组)和 2011-2014 年(第 2 组)。

结果

10844 例患者纳入分析。患者平均年龄为 43 岁(范围 18-50 岁),35%为女性。第 2 组(52%)肥胖(BMI>30)患者明显多于第 1 组(47%)。第 2 组腹腔镜手术和急诊手术及穿孔率明显更高。第 2 组术后感染明显减少。第 2 组术后器官/空间感染和医疗并发症明显更高。

结论

近年来,对于有憩室炎病史的年轻患者,选择性结肠切除术的治疗方法已从更激进转变为更保守。越来越多年轻的憩室炎手术患者为男性且肥胖,术后医疗并发症发生率也有所增加。腹腔镜方法更为常见,手术时间延长,伤口感染率降低。急诊手术和穿孔率增加可能是由于治疗方法的改变,选择性切除术减少。

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