Cardote Teresa A F, Barata Joana F B, Amador Carolina, Alves Eliana, Neves Maria Graça P M S, Cavaleiro José A S, Cunha Ângela, Almeida Adelaide, Faustino Maria Amparo F
Department of Chemistry, University of Aveiro, Aveiro, Portugal.
Centro de Estudos do Ambiente e do Mar, Department of Biology, University of Aveiro, Aveiro, Portugal.
An Acad Bras Cienc. 2018;90(1 Suppl 2):1175-1185. doi: 10.1590/0001-3765201820170824.
Cationic derivatives of 5,10,15-tris[4-(pyridin-4-ylsulphanyl)-2,3,5,6-tetrafluorophenyl]-corrolategallium(III)pyridine and 5,10,15-tris[4-(pyridin-2-ylsulfanyl)-2,3,5,6-tetrafluorophenyl]-correlategallium(III)pyridine were synthesized and their photosensitizing properties against the naturally bioluminescent Gram-negative bacterium Allivibrio fischeri were evaluated. The cationic corrole derivatives exhibited antibacterial activity at micromolar concentrations against this Gram-negative bacterium strain.
合成了5,10,15-三[4-(吡啶-4-基硫烷基)-2,3,5,6-四氟苯基]-卟啉镓(III)吡啶和5,10,15-三[4-(吡啶-2-基硫烷基)-2,3,5,6-四氟苯基]-卟啉镓(III)吡啶的阳离子衍生物，并评估了它们对天然生物发光革兰氏阴性菌费氏弧菌的光敏性质。这些阳离子卟啉衍生物在微摩尔浓度下对该革兰氏阴性菌菌株表现出抗菌活性。
