Andersen Rosa Marie, Henriksen Daniel P, Mafi Hossein Mohit, Langfeldt Sten, Budtz-Lilly Jacob, Graumann Ole
1 Department of Radiology, Aarhus University Hospital, Aarhus, Denmark.
2 Department of Vascular Surgery, Aarhus University Hospital, Aarhus, Denmark.
Vasc Endovascular Surg. 2018 Oct;52(7):505-511. doi: 10.1177/1538574418779667. Epub 2018 Jun 6.
The aim of this study was to evaluate the incidence, risk factors, and outcome of endoleaks related to endovascular aneurysm repair (EVAR) procedure at a single center with up to 10 years' surveillance.
All patients treated with EVAR for an abdominal aorta or iliac aneurysm in a 10-year period at a single cardiovascular center in Denmark were included. Data were collected from a national database and patient journals. Follow-up computed tomography angiography and plain abdominal X-ray reports were reviewed.
A total of 421 patients were included. There were 125 endoleaks observed in 117 (27.8%) patients after a median 95 days (interquartile range: 90-106 days). There were 16 type I, 107 type II, 1 type III, and 1 type V endoleaks. A total of 33 (7.8%) patients had at least 1 reintervention. Patients with type II endoleaks had significantly fewer active smokers and lower plasma creatinine at baseline. They also more often had one, or both, internal iliac arteries embolized as well as an identified endoleak at the procedural completion angiogram. Non-type II endoleaks were associated with internal iliac artery embolization. There was no association between the occurrence of endoleaks and increased mortality.
Type II endoleaks are common after EVAR, yet few lead to reintervention. Absence of smoking, low plasma creatinine, embolized iliac arteries, and endoleak on completion angiogram were associated with type II endoleaks, whereas only embolized iliac arteries were associated with non-type II endoleaks. Overall, endoleaks are not associated with increased mortality.
本研究旨在评估在单一中心进行长达10年监测的血管内动脉瘤修复(EVAR)手术相关内漏的发生率、危险因素及预后。
纳入丹麦一个心血管中心10年间接受EVAR治疗腹主动脉或髂动脉瘤的所有患者。数据从国家数据库和患者病历中收集。回顾随访计算机断层扫描血管造影和腹部平片报告。
共纳入421例患者。117例(27.8%)患者术后中位95天(四分位间距:90 - 106天)观察到125例内漏。其中I型内漏16例,II型内漏107例,III型内漏1例,V型内漏1例。共有33例(7.8%)患者至少接受1次再次干预。II型内漏患者基线时现吸烟者显著较少,血浆肌酐较低。他们也更常出现一侧或双侧髂内动脉栓塞,以及在手术完成血管造影时发现内漏。非II型内漏与髂内动脉栓塞有关。内漏的发生与死亡率增加无关。
EVAR术后II型内漏常见,但很少导致再次干预。不吸烟、低血浆肌酐、髂动脉栓塞以及手术完成血管造影时出现内漏与II型内漏有关,而只有髂动脉栓塞与非II型内漏有关。总体而言,内漏与死亡率增加无关。