Center for Applied Genomics and Precision Medicine, Department of Medicine, Duke University School of Medicine, Durham, North Carolina, USA.
Programme in Health Services and Systems Research, Duke-NUS Medical School, Singapore, Singapore.
Genet Med. 2019 Feb;21(2):331-338. doi: 10.1038/s41436-018-0049-x. Epub 2018 Jun 6.
This paper describes the implementation outcomes associated with integrating a family health history-based risk assessment and clinical decision support platform within primary care clinics at four diverse healthcare systems.
A type III hybrid implementation-effectiveness trial. Uptake and implementation processes were evaluated using the Reach, Effectiveness, Adoption, Implementation, and Maintenance (RE-AIM) framework.
One hundred (58%) primary care providers and 2514 (7.8%) adult patients enrolled. Enrolled patients were 69% female, 22% minority, and 32% Medicare/Medicaid. Compared with their respective clinic's population, patient-participants were more likely to be female (69 vs. 59%), older (mean age 57 vs. 49), and Caucasian (88 vs. 69%) (all p values <0.001). Female (81.3% of females vs. 78.5% of males, p value = 0.018) and Caucasian (Caucasians 90.4% vs. minority 84.1%, p value = 0.02) patient-participants were more likely to complete the study once enrolled. Patient-participant survey responses indicated MeTree was easy to use (95%), and patient-participants would recommend it to family/friends (91%). Minorities and those with less education reported greatest benefit. Enrolled providers reflected demographics of underlying provider population.
Family health history-based risk assessment can be effectively implemented in diverse primary care settings and can effectively engage patients and providers. Future research should focus on finding better ways to engage young adults, males, and minorities in preventive healthcare.
本文描述了在四个不同医疗保健系统的基层医疗诊所中整合基于家族健康史的风险评估和临床决策支持平台的实施结果。
这是一项 III 型混合实施效果试验。采用 RE-AIM(实施范围、有效性、适用性、实施和维持)框架评估了参与度和实施过程。
有 100 名(58%)初级保健提供者和 2514 名(7.8%)成年患者入组。入组患者中 69%为女性,22%为少数民族,32%为医疗保险/医疗补助患者。与各自诊所的人群相比,患者参与者更有可能为女性(69%比 59%,p 值<0.001)、年龄更大(平均年龄 57 岁比 49 岁,p 值<0.001)和白种人(88%比 69%,p 值<0.001)。女性(女性患者中 81.3%比男性患者中 78.5%,p 值=0.018)和白种人(白种人患者中 90.4%比少数民族患者中 84.1%,p 值=0.02)患者参与者完成研究的可能性更大。患者参与者的调查回复表明,MeTree 使用方便(95%),并且他们会向家人/朋友推荐(91%)。少数民族和受教育程度较低的患者报告受益最大。入组的提供者反映了基础提供者人群的人口统计学特征。
基于家族健康史的风险评估可以在不同的基层医疗环境中有效实施,并能有效地吸引患者和提供者。未来的研究应集中在寻找更好的方法来吸引年轻成年人、男性和少数民族参与预防保健。