Menon Leena Unnikrishnan, Varma R Balagopal, Kumaran Parvathy, Xavier Arun Mamachan, Govinda Bhat Sangeetha, Kumar J Suresh
Department of Pedodontics, Amrita School of Dentistry, Amrita Vishwa Vidyapeetham, Kochi, Kerala, India.
Contemp Clin Dent. 2018 Apr-Jun;9(2):151-157. doi: 10.4103/ccd.ccd_562_17.
To evaluate and compare the efficacy of "calcium sucrose phosphate" (CaSP) toothpaste (Enafix 5%) with ordinarily used calcium, phosphate-containing toothpaste in elevating the level of calcium, phosphate ions in saliva. Secondary aims were to evaluate substantivity and plaque-reducing ability of CaSP toothpaste.
Thirty study participants of age group 6-13 years were divided into two groups: Group X (Control group) was made to continue brushing with their regularly used calcium, phosphate-containing toothpaste and Group Y (Test group) was allotted CaSP toothpaste. 1 ml of unstimulated saliva was periodically collected from both groups to determine any alteration in the salivary calcium, phosphate level. Parameters such as substantivity and plaque-reducing ability of CaSP toothpaste were also evaluated. Salivary mineral's intergroup comparison was evaluated by Student's -test while its intragroup comparison along with the plaque amount variation in Group Y was evaluated by ANOVA and Tukey's test.
Group Y showed an increase in the salivary calcium level though not statistically significant. The increase was pronounced in samples collected on day 1. Group Y showed a consistent level of calcium, phosphate in samples collected immediately and 6 h postbrushing, indicating its substantivity. In addition, Group Y had an impact in reducing the plaque level when the 1-month plaque score was compared with the 12-month score.
CaSP leads to an increase in the salivary calcium level though it was not statistically significant. Supervised brushing and dietary habits showed a positive effect on both the groups. CaSP toothpaste also showed substantivity and plaque-reducing ability.
评估并比较“磷酸蔗糖钙”（CaSP）牙膏（Enafix 5%）与常用的含钙、磷牙膏在提高唾液中钙、磷离子水平方面的功效。次要目的是评估CaSP牙膏的附着性和减少牙菌斑的能力。
30名年龄在6至13岁的研究参与者被分为两组：X组（对照组）继续使用其常用的含钙、磷牙膏刷牙，Y组（试验组）使用CaSP牙膏。定期从两组收集1毫升未刺激唾液，以确定唾液中钙、磷水平的任何变化。还评估了CaSP牙膏的附着性和减少牙菌斑能力等参数。两组间唾液矿物质的比较采用学生t检验，而组内比较以及Y组牙菌斑量的变化采用方差分析和Tukey检验。
Y组唾液钙水平有所升高，尽管无统计学意义。在第1天收集的样本中升高较为明显。Y组在刷牙后立即和6小时收集的样本中钙、磷水平保持一致，表明其具有附着性。此外，当将1个月的牙菌斑评分与12个月的评分进行比较时，Y组在降低牙菌斑水平方面有影响。
CaSP导致唾液钙水平升高，尽管无统计学意义。监督刷牙和饮食习惯对两组均显示出积极影响。CaSP牙膏还显示出附着性和减少牙菌斑的能力。
