Semaan D G, Igoli J O, Young L, Marrero E, Gray A I, Rowan E G
Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, 161 Cathedral Street, Glasgow G4 0RE, United Kingdom.
Department of Chemistry, University of Agriculture, PMB 2373 Makurdi, Nigeria.
Data Brief. 2018 Feb 3;17:401-406. doi: 10.1016/j.dib.2018.01.057. eCollection 2018 Apr.
The data presented in this article are related to the research article under the title "in vitro anti-diabetic activity of flavonoids and pheophytins from Sw. on PTP1B, DPPIV, alpha-glucosidase and alpha-amylase enzymes" (Semaan et al., 2017) [3]. This article defines the kinetics of inhibition of flavonoids and pheophytin A extracts from which showed an inhibition of the PTP1B enzyme activity. The main reason to make these results public is to confirm that this study was followed up and no more experiments are needed, also to confirm that these compounds can be reported as PTP1B inhibitors.
本文所呈现的数据与标题为“来自Sw.的黄酮类化合物和脱镁叶绿素对蛋白酪氨酸磷酸酶1B、二肽基肽酶IV、α-葡萄糖苷酶和α-淀粉酶的体外抗糖尿病活性”的研究文章相关(Semaan等人,2017年)[3]。本文定义了黄酮类化合物和脱镁叶绿素A提取物的抑制动力学,其显示出对蛋白酪氨酸磷酸酶1B酶活性的抑制作用。公开这些结果的主要原因是为了确认该研究已得到跟进且无需更多实验,同时也为了确认这些化合物可作为蛋白酪氨酸磷酸酶1B抑制剂进行报道。