Afouda Boni A, Lynch Adam T, de Paiva Alves Eduardo, Hoppler Stefan
Institute of Medical Sciences, Foresterhill Health Campus, University of Aberdeen, Scotland, UK.
Centre for Genome-Enabled Biology and Medicine, King's College Campus, University of Aberdeen, Scotland, UK.
Data Brief. 2018 Jan 17;17:559-563. doi: 10.1016/j.dib.2018.01.005. eCollection 2018 Apr.
The transcription factors GATA4, GATA5 and GATA6 play important roles in heart muscle differentiation. The data presented in this article are related to the research article entitled "Genome-wide transcriptomics analysis identifies sox7 and sox18 as specifically regulated by gata4 in cardiomyogenesis" (Afouda et al., 2017) [1]. The present study identifies genes regulated by these individual cardiogenic GATA factors using genome-wide transcriptomics analysis. We have presented genes that are specifically regulated by each of them, as well those regulated by either of them. The gene ontology terms (GO) associated with the genes differentially affected are also presented. The data set will allow further investigations on the gene regulatory network downstream of individual cardiogenic GATA factors during cardiac muscle formation.
转录因子GATA4、GATA5和GATA6在心肌分化过程中发挥着重要作用。本文所呈现的数据与题为《全基因组转录组学分析确定sox7和sox18在心肌发生过程中受gata4特异性调控》（阿福达等人，2017年）[1]的研究论文相关。本研究通过全基因组转录组学分析确定了受这些个体心脏发生GATA因子调控的基因。我们展示了分别受它们各自调控的基因，以及受它们其中之一调控的基因。还呈现了与差异受影响基因相关的基因本体术语（GO）。该数据集将有助于进一步研究个体心脏发生GATA因子下游在心肌形成过程中的基因调控网络。
