Lyu Lihua, Wang Qiufeng, Song Shujie, Zhou Huaibin, Li Ming, Zhou Chen, Jiang Zhiying, Li Liyan, Lyu Jianxin, Chen Guorong, Bai Yidong
School of Laboratory Medicine and Life Sciences, Key Laboratory of Laboratory Medicine, Ministry of Education, Zhejiang Provincial Key Laboratory of Medical Genetics, Wenzhou Medical University, Wenzhou 325035, Zhejiang, China.
Department of Pathology, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, China.
Data Brief. 2018 Feb 16;17:1149-1152. doi: 10.1016/j.dib.2018.02.040. eCollection 2018 Apr.
This dataset presents the mitochondrial genome variants associated with oncocytic tumors. These data were obtained by Sanger sequencing of the whole mitochondrial genomes of oncocytic tumors and the adjacent normal tissues from 32 patients. The mtDNA variants are identified after compared with the revised Cambridge sequence, excluding those defining haplogroups of our patients. The pathogenic prediction for the novel missense variants found in this study was performed with the Mitimpact 2 program.
该数据集展示了与嗜酸细胞瘤相关的线粒体基因组变异。这些数据是通过对32例患者的嗜酸细胞瘤及其相邻正常组织的整个线粒体基因组进行桑格测序获得的。将线粒体DNA变异与修订后的剑桥序列进行比较后进行鉴定，排除了定义我们患者单倍群的那些变异。本研究中发现的新型错义变异的致病性预测是使用Mitimpact 2程序进行的。
