Riley Robert, Nagy Laszlo
United States Department of Energy Joint Genome Institute, Walnut Creek, CA, USA.
Institute of Biochemistry, Biological Research Centre of the Hungarian Academy of Sciences, Szeged, Hungary.
Methods Mol Biol. 2018;1775:251-266. doi: 10.1007/978-1-4939-7804-5_20.
Phylogenomics aims to infer the evolutionary relationships of organisms, and their genomes, genes, and proteins, from genomic data. Understanding the evolution of these components can provide clues about their biological functions. Here we describe minimal protocols for inferring families of genes (and the proteins they encode), and using them in phylogenomic analyses to infer species trees.
系统发育基因组学旨在从基因组数据中推断生物体及其基因组、基因和蛋白质的进化关系。了解这些组成部分的进化可以为它们的生物学功能提供线索。在这里，我们描述了推断基因家族（及其编码的蛋白质）并将其用于系统发育基因组分析以推断物种树的最小化方案。
