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黏蛋白 5AC 水平与呼吸道合胞病毒疾病严重程度相关。

MUC5AC Levels Associated With Respiratory Syncytial Virus Disease Severity.

机构信息

Department of Pediatrics, Emory University and Children's Healthcare of Atlanta, Georgia.

Fundacion INFANT, Buenos Aires, Argentina.

出版信息

Clin Infect Dis. 2018 Oct 15;67(9):1441-1444. doi: 10.1093/cid/ciy340.

DOI:10.1093/cid/ciy340
PMID:29878077
Abstract

To assess MUC5AC as a biomarker for respiratory syncytial virus (RSV) disease severity, we tested nasal aspirates from RSV+ children with mild, moderate, and severe disease. Levels were significantly higher in those in the severe and moderate groups compared to mild group, indicating MUC5AC may be a useful biomarker for RSV disease severity.

摘要

为了评估黏蛋白 5AC（MUC5AC）作为呼吸道合胞病毒（RSV）疾病严重程度的生物标志物，我们检测了患有轻度、中度和重度 RSV 疾病的儿童的鼻抽吸物。与轻度组相比，严重组和中度组的水平明显更高，表明 MUC5AC 可能是 RSV 疾病严重程度的有用生物标志物。

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