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补充资料:在生产动物中控制传染病的当前研究空白。

DISCONTOOLS supplement: Current research gaps for advancing control of infectious diseases in production animals.

机构信息

AnimalhealthEurope, Brussels, Belgium.

Kreavet, Kruibeke, Belgium.

出版信息

Transbound Emerg Dis. 2018 May;65 Suppl 1:5-8. doi: 10.1111/tbed.12878.

DOI:10.1111/tbed.12878
PMID:29878664
Abstract

DISCONTOOLS (DISease CONtrol TOOLS) is an open-access database to assist public and private funders of animal health research in identifying research gaps and planning future research. This database is supported by a range of national funders of animal health research in Europe, with industry providing secretariat support. Information in the database is generated by disease-specific expert groups. In this DISCONTOOLS Supplement, contributing experts expanded their gap analyses into review papers for 15 diseases, covering zoonotic, production and epizootic diseases. Across this diverse array of diseases, it is clear that fundamental research on host-pathogen relationships and immune responses remains critical for evidence-based development of novel vaccines, pharmaceuticals and diagnostics to improve animal health. Furthermore, it is also obvious that there is need to better utilize economics and knowledge regarding "human factors" to optimise uptake and use of a broad range of tools and insights.

摘要

DISCONTOOLS(疾病控制工具)是一个开放获取的数据库,旨在帮助公共和私人动物健康研究资助者识别研究空白,并规划未来的研究。该数据库得到了欧洲一系列国家动物健康研究资助者的支持,行业提供秘书处支持。数据库中的信息由特定疾病的专家组生成。在这个 DISCONTOOLS 增刊中,参与的专家将他们的差距分析扩展为 15 种疾病的综述论文,涵盖了人畜共患病、生产和流行疾病。在这一系列不同的疾病中,很明显,宿主-病原体关系和免疫反应的基础研究仍然是基于证据开发新型疫苗、药物和诊断方法以改善动物健康的关键。此外,显然还需要更好地利用经济学和关于“人为因素”的知识,以优化广泛工具和见解的采用和使用。

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