University of Oulu, Medical Research Centre, Research Unit of Surgery, Anaesthesia and Intensive Care and Department of Anaesthesiology, Division of Intensive Care, Oulu University Hospital, PO BOX 21, FI-90029 OYS, Oulu, Finland.
University of Helsinki and Department of Anaesthesiology and Intensive Care, Helsinki University Central Hospital, HUS, FI-00029, Helsinki, Finland.
Scand J Trauma Resusc Emerg Med. 2018 Jun 7;26(1):48. doi: 10.1186/s13049-018-0514-1.
The prehospital research field has focused on studying patient survival in cardiac arrest, as well as acute coronary syndrome, stroke, and trauma. There is little known about the overall short-term mortality and its predictability in unselected prehospital patients. This study examines whether a prehospital National Early Warning Score (NEWS) predicts 1-day and 30-day mortalities.
Data from all emergency medical service (EMS) situations were coupled to the mortality data obtained from the Causes of Death Registry during a six-month period in Northern Finland. NEWS values were calculated from first clinical parameters obtained on the scene and patients were categorized to the low, medium and high-risk groups accordingly. Sensitivities, specificities, positive predictive values (PPVs), negative predictive values (NPVs), and likelihood ratios (PLRs and NLRs) were calculated for 1-day and 30-day mortalities at the cut-off risks.
A total of 12,426 EMS calls were included in the study. The overall 1-day and 30-day mortalities were 1.5 and 4.3%, respectively. The 1-day mortality rate for NEWS values ≤12 was lower than 7% and for values ≥13 higher than 20%. The high-risk NEWS group had sensitivities for 1-day and 30-day mortalities 0.801 (CI 0.74-0.86) and 0.42 (CI 0.38-0.47), respectively.
In prehospital environment, the high risk NEWS category was associated with 1-day mortality well above that of the medium and low risk NEWS categories. This effect was not as noticeable for 30-day mortality. The prehospital NEWS may be useful tool for recognising patients at early risk of death, allowing earlier interventions and responds to these patients.
院前研究领域一直致力于研究心脏骤停、急性冠状动脉综合征、中风和创伤患者的生存率。对于未选择的院前患者的总体短期死亡率及其可预测性知之甚少。本研究探讨了院前国家早期预警评分(NEWS)是否可预测 1 天和 30 天的死亡率。
在芬兰北部六个月的时间内,将所有急救医疗服务(EMS)情况的数据与从死因登记处获得的死亡率数据进行了配对。根据现场获得的最初临床参数计算 NEWS 值,并相应地将患者分为低、中、高危组。计算了各风险组 1 天和 30 天死亡率的截断风险的敏感性、特异性、阳性预测值(PPV)、阴性预测值(NPV)和似然比(PLR 和 NLR)。
共纳入 12426 例 EMS 呼叫。总体 1 天和 30 天死亡率分别为 1.5%和 4.3%。NEWS 值≤12 的 1 天死亡率低于 7%,而≥13 的死亡率高于 20%。高危 NEWS 组的 1 天和 30 天死亡率的敏感性分别为 0.801(95%CI:0.74-0.86)和 0.42(95%CI:0.38-0.47)。
在院前环境中,高危 NEWS 类别与 1 天死亡率相关,明显高于中低危 NEWS 类别。对于 30 天死亡率,这种影响并不明显。院前 NEWS 可能是识别早期死亡风险患者的有用工具,可对这些患者进行更早的干预和响应。