Cheng Hsin-Yi, Lin Bao-Liang, Tseng Jen-Yu, Ueno Kazunori, Nakada Sakura
Department of Obstetrics and Gynecology, Taipei Veterans General Hospital, Taipei, Taiwan.
Department of Obstetrics and Gynecology, Kawasaki Municipal Hospital, Kawasaki, Japan.
Taiwan J Obstet Gynecol. 2018 Jun;57(3):379-382. doi: 10.1016/j.tjog.2018.04.009.
Hysteroscopy has widely been used for diagnosis of the uterine cavity; however, target biopsy has often been difficult in part to the inherent limitations of ancillary instruments. Lin's biopsy grasper was specifically designed to work in conjunction with a flexible hysteroscope to obtain intrauterine biopsy under transabdominal sonography. Herein, we share our clinical experience in the management of endometrial abnormalities with the use of Lin's biopsy grasper during office-based hysteroscopy.
From February 2006 to November 2016, the use of Lin's biopsy grasper for tissue biopsy was attempted on 126 cases. We retrospectively recorded and analyzed the patients' preoperative characteristics and biopsy outcomes to demonstrate the feasibility and efficacy of Lin's biopsy grasper.
Out of the one hundred and twenty-six enrolled patients, satisfactory targeted biopsies were achieved; including high diagnostic rate (92.1%, with 116 cases confirmed histologically) and adequate tissue retrieval (77.8%, with 98 cases obtaining optimal specimen volume). All patients tolerated the procedure without analgesics or anesthesia.
Diagnostic flexible hysteroscopy combined with the use of Lin's biopsy grasper has proven to be an effective tool for intrauterine evaluation and obtaining tissue sample.
宫腔镜已广泛用于宫腔诊断；然而，由于辅助器械的固有局限性，靶向活检往往很困难。林氏活检钳是专门设计用于与软性宫腔镜配合使用，在经腹超声引导下进行宫内活检。在此，我们分享在门诊宫腔镜检查中使用林氏活检钳处理子宫内膜异常的临床经验。
2006年2月至2016年11月，对126例患者尝试使用林氏活检钳进行组织活检。我们回顾性记录并分析患者的术前特征和活检结果，以证明林氏活检钳的可行性和有效性。
在126例入选患者中，实现了满意的靶向活检；包括高诊断率（92.1%，116例经组织学证实）和足够的组织获取量（77.8%，98例获得最佳标本量）。所有患者在无镇痛或麻醉的情况下耐受该操作。
诊断性软性宫腔镜检查联合使用林氏活检钳已被证明是宫内评估和获取组织样本的有效工具。
