Zaghba Nahid, Hachimi Kawtar El, Benjelloun Hanane, Yassine Najiba
Service des Maladies Respiratoires, CHU Ibn Rochd, Casablanca, Maroc.
Pan Afr Med J. 2017 Nov 17;28:241. doi: 10.11604/pamj.2017.28.241.13876. eCollection 2017.
Alveolar microlithiasis (AM) is a rare disease, characterized by the accumulation of calcium concretions in the pulmonary alveolar lumen. We report a new case of AM suspected on chest X-ray and confirmed by chest CT scan, whose appearance was pathognomonic, and by transbronchial pulmonary biopsy. AM is often asymptomatic, contrasting with the importance of lesions on X-ray which are characteristics of this disease. The cause of this disease is unknown. However autosomal recessive inheritance with mutation in the SLC34A2 gene is suspected.
肺泡微石症(AM)是一种罕见疾病,其特征是肺泡腔内有钙盐沉着。我们报告一例经胸部X线怀疑并经胸部CT扫描确诊的肺泡微石症新病例,其表现具有特征性,且通过经支气管肺活检得以证实。肺泡微石症通常无症状,这与X线显示的具有该疾病特征的病变的严重性形成反差。该疾病的病因尚不清楚。然而,怀疑是由SLC34A2基因突变引起的常染色体隐性遗传。