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以色列初级保健中的传染病负担和抗生素处方

Infectious disease burden and antibiotic prescribing in primary care in Israel.

机构信息

Clalit Research Institute & Chief Physician's Office, Clalit Health Services, Tel Aviv, Israel.

School of Public Health, University of Haifa, Haifa, Israel.

出版信息

Ann Clin Microbiol Antimicrob. 2018 Jun 9;17(1):26. doi: 10.1186/s12941-018-0278-5.

Abstract

BACKGROUND

Antibiotics are frequently prescribed at many of the visits to primary care clinics, often for conditions for which they provide no benefit, including viral respiratory tract infections.

OBJECTIVES

The aim was to evaluate primary care visits due to infectious diseases, and to estimate antibiotic prescribing and antibiotic dispensing by pharmacies.

METHODS

Diagnosis of infectious disease, antibiotic prescribing and dispensing data at the individual patient level were extracted for 2015 from Clalit Health Services' electronic medical records and linked to determine the condition for which the antimicrobial was prescribed.

RESULTS

There were 6.6 million visits due to infections, representing 22% of all primary care visits. The most common events were upper respiratory tract infections (38%) and pharyngitis (10%). Highest prescription rates were for urinary tract infections (80%), otitis media (64%), pharyngitis (71%), sinusitis (63%), and lower respiratory tract infections (76%). The highest rates of undispensed prescriptions were for acute gastroenteritis, urinary tract infections, and pharyngitis (24, 23, and 16%, respectively).

CONCLUSIONS

Infectious diseases constitute a heavy burden on primary care, with overprescribing of antibiotics. Intervention to reduce unwarranted antibiotic use is needed. In pediatric care, interventions should focus on better controlling antibiotic consumption and encouraging adherence to guidelines for upper respiratory tract infections, pharyngitis, and otitis media. In adults interventions should aim to monitor antibiotic prescribing for upper respiratory tract infections and improve adherence to guidelines for urinary tract infections.

摘要

背景

抗生素经常在许多基层医疗机构就诊时开具,通常用于治疗它们没有益处的疾病,包括病毒性呼吸道感染。

目的

评估因传染病就诊的情况,并估计药店开具和配药的抗生素数量。

方法

从 Clalit 医疗保健服务机构的电子病历中提取了 2015 年个人患者水平的传染病诊断、抗生素开具和配药数据,并进行了链接,以确定开具抗菌药物的疾病。

结果

有 660 万次因感染导致的就诊,占所有基层医疗就诊的 22%。最常见的事件是上呼吸道感染(38%)和咽炎(10%)。抗生素处方率最高的是尿路感染(80%)、中耳炎(64%)、咽炎(71%)、鼻窦炎(63%)和下呼吸道感染(76%)。未配药的处方率最高的是急性肠胃炎、尿路感染和咽炎(24%、23%和 16%)。

结论

传染病给基层医疗带来了沉重负担,抗生素的过度使用情况严重。需要采取干预措施来减少不必要的抗生素使用。在儿科护理中,干预措施应侧重于更好地控制抗生素的消耗,并鼓励遵守上呼吸道感染、咽炎和中耳炎的指南。在成人中,干预措施应旨在监测上呼吸道感染的抗生素处方,并提高尿路感染指南的遵守率。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d111/5994243/05669a832007/12941_2018_278_Fig1_HTML.jpg

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