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睫状体环扎联合改良部分睫状体平坦部玻璃体切除术治疗恶性青光眼的临床疗效。

Clinical Efficacy of Ciliary Ring Incision Combined with Modified Partial Pars Plana Vitrectomy for Malignant Glaucoma.

机构信息

Department of Ophthalmology, Wuxi No. 9 People's Hospital Affiliated to Soochow University, Wuxi, Jiangsu, China (mainland).

出版信息

Med Sci Monit. 2018 Jun 10;24:3916-3921. doi: 10.12659/MSM.910672.

Abstract

BACKGROUND Currently, safe and effective surgical treatment of malignant glaucoma is still under investigation. This study evaluated the clinical efficacy of ciliary ring incision combined with modified partial pars plana vitrectomy in the treatment of malignant glaucoma. The technique is particularly useful in the treatment of "phakic" patients with malignant glaucoma, especially those who wish to preserve the natural lens. MATERIAL AND METHODS We retrospectively analyzed 13 cases (16 eyes) of malignant glaucoma in which patients underwent ciliary ring incision combined with modified partial pars plana vitrectomy based on follow-up data collected from May 2004 to March 2017. The data we analyzed included postoperative best-corrected visual acuity(BCVA), intraocular pressure (IOP), anterior chamber depth (ACD), optic cup changes, and surgical complications; some patients underwent visual field tracking. The mean follow-up period was 33.1±10.6 (range, 19-46) months. RESULTS A statistically significant number of eyes had improved visual acuity 1 year after surgery compared with the preoperative difference (Z=-3.853, P=0.000). Increases in the mean anterior chamber depth and decreases in the mean IOP measured at the 1-week and the 1-year follow-ups were also statistically significant. There were no serious complications during the follow-up period. CONCLUSIONS Ciliary ring incision combined with modified partial pars plana vitrectomy for malignant glaucoma not only provided a clear and reliable intraoperative vitrectomy channel, but it also caused less disturbance of intraocular tissue structure and fewer complications. It also has the advantage of preserving the lens and avoiding further damage to the anatomy in the anterior segment of the eye.

摘要

背景

目前,恶性青光眼的安全有效手术治疗仍在研究中。本研究评估了睫状体环切开联合改良部分睫状体平坦部玻璃体切除术治疗恶性青光眼的临床疗效。该技术特别适用于“有晶状体”恶性青光眼患者的治疗,尤其是那些希望保留自然晶状体的患者。

材料和方法

我们回顾性分析了 2004 年 5 月至 2017 年 3 月期间,根据随访资料,对 13 例(16 只眼)接受睫状体环切开联合改良部分睫状体平坦部玻璃体切除术治疗的恶性青光眼患者进行了分析。分析的数据包括术后最佳矫正视力(BCVA)、眼压(IOP)、前房深度(ACD)、视杯变化和手术并发症;部分患者进行了视野追踪。平均随访时间为 33.1±10.6 个月(范围 19-46 个月)。

结果

与术前相比,术后 1 年视力明显提高(Z=-3.853,P=0.000)。术后 1 周和 1 年时,平均前房深度增加,平均 IOP 降低,差异有统计学意义。随访期间无严重并发症。

结论

睫状体环切开联合改良部分睫状体平坦部玻璃体切除术治疗恶性青光眼,不仅提供了清晰可靠的术中玻璃体切除通道,而且对眼内组织结构的干扰较小,并发症较少。该方法还具有保留晶状体和避免进一步损害眼前节解剖结构的优点。

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