Dutoit C, Reynier M, Aquaron R
Bull Cancer. 1985;72(2):75-9.
Using calmodulin antibody, evidence for the presence of calmodulin, a calcium-binding protein modulator of numerous enzymes was shown by indirect immunofluorescence in 9 cell lines of cultured human malignant melanocytes. Calmodulin was localized in cytoplasm and in higher concentration in the perinuclear region. These observations agree with the distribution of calmodulin-binding proteins in cytoplasm and membranes.
使用钙调蛋白抗体,通过间接免疫荧光法在9种培养的人恶性黑色素瘤细胞系中证实了钙调蛋白(一种众多酶的钙结合蛋白调节剂)的存在。钙调蛋白定位于细胞质中,且在核周区域浓度更高。这些观察结果与钙调蛋白结合蛋白在细胞质和细胞膜中的分布情况相符。