Chen Cindy, Wulff Regina T, Sholle Evan T, Roboz Gail J, Kraemer David A, Campion Thomas R
Information Technologies and Services Department, Weill Cornell Medicine, New York, NY.
Department of Medicine, Weill Cornell Medicine, New York, NY.
AMIA Jt Summits Transl Sci Proc. 2018 May 18;2017:55-62. eCollection 2018.
To enable clinical and translational research, academic medical centers increasingly implement biospecimen information management systems. At our institution, one laboratory successfully implemented a multi-system solution that enabled collection and reporting of specimen- and aliquot-level data. The objective of this study was to assess the solution against the laboratory's requirements and with respect to support of best practices for biospecimen information management systems defined by the International Society for Biological and Environmental Repositories (ISBER). The solution supported the laboratory's reporting needs and 90% (n=26) of ISBER best practices. To the best of our knowledge, this is among the first studies to demonstrate the generalizability of a biospecimen informatics approach. Findings suggest that development and evaluation of biospecimen informatics approaches can potentially improve through closer collaboration of informatics and biorepository professional societies.
为推动临床和转化研究，学术医疗中心越来越多地实施生物样本信息管理系统。在我们机构，一个实验室成功实施了一个多系统解决方案，该方案能够收集和报告样本及分装水平的数据。本研究的目的是根据实验室的要求，并参照国际生物和环境样本库协会（ISBER）定义的生物样本信息管理系统最佳实践，对该解决方案进行评估。该解决方案满足了实验室的报告需求，并符合90%（n = 26）的ISBER最佳实践。据我们所知，这是首批证明生物样本信息学方法具有通用性的研究之一。研究结果表明，通过信息学和生物样本库专业协会更紧密的合作，生物样本信息学方法的开发和评估可能会得到改善。
