Jiangsu Key Laboratory of Crop Genetics and Physiology/Co-Innovation Center for Modern Production Technology of Grain Crops, Yangzhou University , Yangzhou , China.
Joint International Research Laboratory of Agriculture & Agri-Product Safety of Ministry of Education of China, Yangzhou University , Yangzhou , China.
Nat Prod Res. 2019 Dec;33(23):3398-3403. doi: 10.1080/14786419.2018.1479704. Epub 2018 Jun 11.
Two new phenolic glycoside compounds (, ) and ten known analogues (-) have been isolated from the ethanolic extract of flowers and identified as 2---d-glucopyranosyl-(1)-(4-methoxyphenyl)ethylene glycol (), 2-(4---d-allopyranosyl)phenyl-ethanol (), 2---d-glucopyranosyl-(1)-phenylethylene glycol (), 2---d-glucopyranosyl-(1)-phenylethylene glycol (), ()--coumaryl---d-glucopyranoside (), phenyl---d-glucopyranoside (), 2-phenylethyl---d-glucopyranoside (), salidroside (), 2-(2-hydroxyphenyl)ethanol---d-glucopyranoside (), 4-methoxybenzyl---d-glucopyranoside (), 2,4,6-trimethoxyphenyl-1---d-glucopyranoside () and sachaliside 1 (). The structures of and , including absolute configurations, were determined by spectroscopic data (H NMR, C NMR, HSQC, HMBC and ORD) and chemical methods. In addition, most of them exhibited inhibitory activity with IC values ranging from 14.43 to 50.20 μM in comparison to the positive control acarbose (IC = 15.76 μM) in intestinal -glucosidase inhibitory activity tests.
从 花的乙醇提取物中分离得到两种新的酚糖苷化合物（、）和十种已知类似物（-），并鉴定为 2---d-吡喃葡萄糖基-（1）-（4-甲氧基苯基）乙烯二醇（）、2-（4---d-吡喃阿拉伯糖基）-苯乙醇（）、2---d-吡喃葡萄糖基-（1）-苯乙基二醇（）、2---d-吡喃葡萄糖基-（1）-苯乙基二醇（）、()--香豆素---d-吡喃葡萄糖苷（）、苯--d-吡喃葡萄糖苷（）、2-苯乙基---d-吡喃葡萄糖苷（）、红景天苷（）、2-（2-羟基苯基）乙醇---d-吡喃葡萄糖苷（）、4-甲氧基苄基---d-吡喃葡萄糖苷（）、2,4,6-三甲氧基苯基-1---d-吡喃葡萄糖苷（）和沙利度醇 1（）。通过光谱数据（H NMR、C NMR、HSQC、HMBC 和 ORD）和化学方法确定了和的结构，包括绝对构型。此外，在肠-β-葡萄糖苷酶抑制活性测试中，与阳性对照阿卡波糖（IC=15.76μM）相比，它们中的大多数都表现出抑制活性，IC 值范围为 14.43 至 50.20μM。
