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晚期慢性阻塞性肺疾病患者的临终策略。

End-of-Life Strategies among Patients with Advanced Chronic Obstructive Pulmonary Disease.

机构信息

1 Department of Medicine and Sunnybrook Research Institute, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada.

2 Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada.

出版信息

Am J Respir Crit Care Med. 2018 Dec 1;198(11):1389-1396. doi: 10.1164/rccm.201803-0592OC.

Abstract

RATIONALE

The burden of advanced chronic obstructive pulmonary disease (COPD) is high globally; however, little is known about how often end-of-life strategies are used by this population.

OBJECTIVES

To describe trends in the use of end-of-life care strategies by people with advanced COPD in Ontario, Canada.

METHODS

A population-based repeated cross-sectional study examining end-of-life care strategies in individuals with advanced COPD was conducted. Annual proportions of individuals who received formal palliative care, long-term oxygen therapy, or opioids from 2004 to 2014 were determined. Results were age and sex standardized and stratified by age, sex, socioeconomic status, urban/rural residence, and immigrant status. Measurement/Main Results: There were 151,912 persons with advanced COPD in Ontario between 2004 and 2014. Use of formal palliative care services increased 1% per year from 5.3% in 2004 to 14.3% in 2014 (P value for trend < 0.001), whereas use of long-term oxygen therapy increased 1.1% per year from 26.4% in 2004 to 35.3% in 2013 (P value for trend < 0.001). The use of opioids was relatively stable (40.0% in 2004 and 41.8% in 2014; P value for trend = 0.08). Younger individuals were less likely to use formal palliative care services and long-term oxygen therapy. Males were less likely than females to receive long-term oxygen therapy and opioids.

CONCLUSIONS

The proportion of people with advanced COPD using end-of-life strategies, although increasing, remains low. Efforts should focus on increasing access to such strategies and educating patients and providers of their benefits.

摘要

背景

全球范围内,晚期慢性阻塞性肺疾病(COPD)的负担很重;然而,对于该人群使用临终策略的频率知之甚少。

目的

描述加拿大安大略省晚期 COPD 患者使用临终关怀策略的趋势。

方法

开展了一项基于人群的反复横断面研究,以研究晚期 COPD 患者的临终关怀策略。确定了 2004 年至 2014 年期间,每年接受正规姑息治疗、长期氧疗或阿片类药物的个体比例。结果经过年龄和性别标准化,并按年龄、性别、社会经济状况、城乡居住和移民身份进行分层。

测量/主要结果:2004 年至 2014 年期间,安大略省有 151912 名晚期 COPD 患者。正规姑息治疗服务的使用每年增加 1%,从 2004 年的 5.3%增加到 2014 年的 14.3%(趋势 P 值<0.001),而长期氧疗的使用每年增加 1.1%,从 2004 年的 26.4%增加到 2013 年的 35.3%(趋势 P 值<0.001)。阿片类药物的使用相对稳定(2004 年为 40.0%,2014 年为 41.8%;趋势 P 值=0.08)。年轻个体不太可能使用正规姑息治疗服务和长期氧疗。男性接受长期氧疗和阿片类药物的可能性低于女性。

结论

尽管使用临终策略的晚期 COPD 患者比例有所增加,但仍很低。应努力增加获得这些策略的机会,并教育患者和提供者了解其益处。

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